Macrocyclic Zn(II) Complexes: Synthesis, Structure and Hydrolysis of p-Nitrophenyl Acetate (pNPA)

Authors

  • S.K. Pandey Department of Chemistry, DDU Gorakhpur University Gorakhpur-273009, Uttar Pradesh
  • M.L. Sharma Department of Chemistry, Tribhuvan University, Tri-Chandra Campus, Kathmandu
  • O.P. Pandey Department of Chemistry, DDU Gorakhpur University Gorakhpur-273009, Uttar Pradesh
  • S.K. Sengupta Department of Chemistry, DDU Gorakhpur University Gorakhpur-273009, Uttar Pradesh

DOI:

https://doi.org/10.3126/jist.v20i2.13947

Keywords:

Macrocyclic ligand, zinc(II) complex, SEM, ester hydrolysis, kinetics

Abstract

A new series of Zn(II) macrocyclic complexes has been synthesized by the reaction of Schiff bases (derived from dihydrazides and benzil/phthalaldehyde) in the presence of zinc(II) acetate dihydrate in ethanol. The complexes have been characterized by means of elemental and spectral (IR, 1H and 13C NMR) and SEM analysis. The kinetic studies were done to study the catalytic properties of these complexes towards the hydrolysis of p-nitrophenylacetate (pNPA) at 25°C in aqueous dimethylsulphoxide using phosphate buffer (pH = 7.0–8.5). During the reaction, absorbance of p-nitrophenolate increases with increase in time (i.e., increase of p-nitrophenolate concentration) which give information about the reaction progress i.e., ester hydrolysis. On the basis of these results, a plausible mechanism for the hydrolysis of pNPA is proposed. It is observed that coordinated water molecule might be serving as a good nucleophile that effectively catalyzes pNPA hydrolysis. Therefore, this type of complexes can be used as hydrolytic model enzymes.

Journal of Institute of Science and Technology, 2015, 20(2): 42-48

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Published

2015-11-26

How to Cite

Pandey, S., Sharma, M., Pandey, O., & Sengupta, S. (2015). Macrocyclic Zn(II) Complexes: Synthesis, Structure and Hydrolysis of p-Nitrophenyl Acetate (pNPA). Journal of Institute of Science and Technology, 20(2), 42–48. https://doi.org/10.3126/jist.v20i2.13947

Issue

Vol. 20 No. 2 (2015)

Section

Research Articles

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