Clinical score to predict the short-term outcome of pediatric status epilepticus
Keywords:
Status epilepticus, STEPSS, OutcomeAbstract
INTRODUCTIONUnlike in adults, clinical scoring system to predict outcome and treatment response in pediatric status epilepticus is lacking. We used a pediatric modification of adult scoring system, Status epilepticus in pediatric patients severity score (STEPSS) to determine if it can accurately predict short term outcome.
MATERIAL AND METHODSIn this prospective study, children aged 1 to 18 years with seizure duration of ≥ 5 minutes or actively convulsing at emergency room were enrolled. STEPSS score was calculated at admission and outcome such as mortality, Pediatric overall performance category (POPC) at discharge and treatment response were noted. The diagnostic utility of STEPSS score to predict unfavorable outcome was calculated.
RESULTSOne hundred and twenty-five children with mean age 5.1 years were enrolled. Seven children died and 29 had unfavorable outcome. The predictive accuracy of STEPSS at cutoff >3 for mortality had sensitivity of 85.3, specificity of 60.2 and negative predictive value of 98.6 with area under curve 0.751 [ 95% CI: 0.593-0.908]). Likewise, it predicted unfavorable outcome with sensitivity of 51.7, specificity of 60.4 and negative predictive value of 80.6.
CONCLUSIONThe STEPSS, a simple bedside clinic score was found to be valuable in predicting outcome and treatment response in children with status epilepticus.
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