Clinical, Socio-Demographic and Biochemical Variables in Patients With Covid-19: A Cross Sectional Study

Abstract

INTRODUCTION

Covid-19 is a debilitating disorder which affects the lungs with multiple organs involvement. The biochemical variables play important role in the management of the Covid-19 patients who are with different clinical profile, socio-demographic, and co-morbid conditions like diabetes and hypertension.

MATERIAL AND METHODS

This cross sectional study was conducted in the Covid-19 hospitalized cases at UCMS, Bhairahawa. Total of 150 patients were enrolled in the study period from May 2021 and October 2021 whose clinical profile, sociodemographic and biochemical variables were assessed.

RESULTS

The gender wise distribution shows the male dominancy with M:F ratio 1:0.85. The maximum age group vulnerable to Covid-19 in our study was found to be 41-60 years with median age of 47 years. There were constellations of symptom with shortness of breath 70% becoming first followed by cough 67.3% and fever 54%. The frequency of diabetes and hypertension was 19.3% and 24% showing co-morbidity associated changes in biochemical parameters. The male to female differences in biochemical changes have been associated with Covid-19 patients, however age wise distribution do not show any difference in biochemical parameters.

CONCLUSION

COVID 19 patients have a high prevalence of diabetes and hypertension, which is a common morbidity. A few biochemical indices (D-dimer, LDH, CRP, and ALT) change significantly between males and females. All biochemical parameters, on the other hand, are unaffected by age.