Antibiotic Resistance in Clinical Medicine

Authors

  • Santosh Shah Universal College of Medical Sciences, Bhairahawa, Nepal
  • Rajeshwar Reddy Kasarla Universal College of Medical Sciences, Bhairahawa, Nepal
  • Nikita Singh Yadav Universal College of Medical Sciences, Bhairahawa, Nepal
  • Anjita Shrestha Universal College of Medical Sciences, Bhairahawa, Nepal
  • Sadhana Gautam Universal College of Medical Sciences, Bhairahawa, Nepal
  • Sushil Kumar Chaudhary Universal College of Medical Sciences, Bhairahawa, Nepal

DOI:

https://doi.org/10.3126/jucms.v10i02.51343

Keywords:

Antibiotic resistance, Mutational drug resistance, Transferable drug resistance

Abstract

Since the discovery of penicillin, antibiotics have been a cornerstone in modern medicine and significantly improved global health. And while decades of overuse, misuse and abuse of antibiotics in hospitals, and in general population, at an ever increasing rate, both when they are needed and when they are not, in human beings and animals have accelerated the emergence and spread of resistant bacteria. Indiscriminate use of antibiotics in veterinary practice, and in animal feeds led to emergence of drug resistant strains, that are transferred to humans. This emergence of drug resistance is a major problem worldwide in antibiotic therapy. Infections caused by resistant microorganisms often fail to respond to the standard treatment, resulting in prolonged illness, longer hospital stays, higher healthcare expenditures, and greater risk of death. This article reviews and focuses on various aspects of development and mechanisms of antibiotic resistance in bacteria, and preventive measures to fight the emerg- ing antibiotic resistance threat.

Downloads

Download data is not yet available.
Abstract
65
PDF
65

Author Biographies

Santosh Shah, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of General Surgery (CTVS)

Rajeshwar Reddy Kasarla, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Microbiology 

Nikita Singh Yadav, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Microbiology

Anjita Shrestha, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Microbiology

Sadhana Gautam, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Microbiology

Sushil Kumar Chaudhary, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Microbiology

Downloads

Published

2022-12-31

How to Cite

Shah, S., Kasarla, R. R., Yadav, N. S., Shrestha, A., Gautam, S., & Chaudhary, S. K. (2022). Antibiotic Resistance in Clinical Medicine. Journal of Universal College of Medical Sciences, 10(02), 66–71. https://doi.org/10.3126/jucms.v10i02.51343

Issue

Section

Review Articles