Lipid profile in psoriasis

Authors

  • Y Poudyal Assistant Professor, Department of Dermatology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa
  • SL Rajbhandari Professor, Department of Dermatology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa

DOI:

https://doi.org/10.3126/jucms.v2i1.10485

Keywords:

Psoriasis, Dyslipidemia, Lipid, Heart disease

Abstract

INTRODUCTION: Psoriasis is a common inflammatory skin disorder. A predisposition to vascular occlusive disease and high prevalence of heart disease has been seen to be associated with psoriasis and it has been suggested that some of these patients have some disorders of lipid metabolism. Dyslipidemia has been suggested in the pathogenesis of this phenomenon.

METHODS: One hundred and six patients were selected for the study. Among them 53 (male=26, female=27) with psoriasis were taken as case and 53 with other dermatologic diseases, after matching for age and sex, were taken as control. The lipid profile that comprised four parameters: serum HDL, LDL-C, TC and TG were determined for both case and control and compared.

RESULTS: It was found that serum TG, TC levels were significantly higher and serum HDL level was significantly lower in patients with psoriasis (P<0.05). When the risk factors like alcoholism and smoking were adjusted, only abnormal serum level of TG and TC were seen to be significantly associated with psoriasis.

CONCLUSION: This study showed that abnormal TG and TC are associated with psoriasis. This fact may be responsible for the high prevalence of cardiovascular events in psoriasis. It may be useful to do early screening and treatment of dyslipidemia to prevent the adverse cardiovascular event.

DOI: http://dx.doi.org/10.3126/jucms.v2i1.10485

Journal of Universal College of Medical Sciences (2014) Vol.2(1): 16-19

Downloads

Download data is not yet available.
Abstract
824
PDF
634

Downloads

Published

2014-05-24

How to Cite

Poudyal, Y., & Rajbhandari, S. (2014). Lipid profile in psoriasis. Journal of Universal College of Medical Sciences, 2(1), 16–19. https://doi.org/10.3126/jucms.v2i1.10485

Issue

Vol. 2 No. 1 (2014)

Section

Original Articles

License

Authors have to give the following undertakings along with their article:

  1. I/we declare that this article is original and has not been submitted to another journal for publication.
  2. I/we declare that I/we surrender all the rights to the editor of the journal and if published will be the property of the journal and we will not publish it anywhere else, in full or part, without the permission of the Chief Editor.
  3. Institutional ethical and research committee clearance certificate from the institution where work/research was done, is required to be submitted.
  4. Articles in the Journal are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)
  5. This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.