Correlation of Biochemical Parameters among Diabetes patients attending Medicine OPD of Janaki Medical College Teaching Hospital

Authors

  • Satyam Prakash Janaki Medical College
  • Om Prakash Yadav Janaki Medical College
  • Vijay Kumar Sah Janaki Medical College
  • Jitendra Kumar Singh Janaki Medical College
  • Bharat Jha Janaki Medical College

DOI:

https://doi.org/10.3126/jmcjms.v10i2.47852

Keywords:

Diabetes mellitus, lipid profile, renal function test

Abstract

Background and objectives: With increasing incidence of diabetes mellitus, the cardiovascular and renal complications associated with it are emerging as major concern. The morbidity and mortality associated with diabetes can be reduced by timely assessment of those risk factors. Our study evaluated lipid profile and renal function test in male and female diabetic patients as well as the correlation among those biochemical parameters.

Materials and methods: Blood sugar, lipid profile and renal function test were assessed in 249 confirmed type 2 diabetic patients attending medicine OPD of Janaki medical college teaching hospital (JMCTH), Ramdaiya-Bhawadi, Dhanusha, Nepal. Independent ‘t’ test was used to observe the gender difference in those parameters and Pierson correlation test was applied to look for correlation among different biochemical parameters.

Results: Significant difference was observed between male and female for FBS (p=0.05) and PPBS (p=0.003). Such significant difference between male and female was also noted for lipid profile parameters, TC (177.65+43.09 and 163.45+35.68 respectively, p=0.05), VLDL-C (33.47+16.51 and 28.83+14.00 respectively, p=0.018) and HDL-C (40.52+10.62 and 37.94+8.07 respectively, p=0.033). According to our study TC, TG, VLDL, LDL, HDL showed significant positive correlation with FBS and PPBS. Likewise, creatinine, urea, uric acid was also positively correlated with FBS and PPBS (p<0.05). Moreover, there was significantly high correlation of uric acid with TC, TG, VLDL, LDL (p<0.05). In addition, there was highly significant correlation between creatinine and sodium.

Conclusion: There was a significant difference for blood sugar and lipid profile among male and female diabetic patients. Correlation was seen between blood sugar and lipid profile; uric acid and lipid profile as well as creatinine and sodium.

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Author Biographies

Satyam Prakash, Janaki Medical College

Department of Biochemistry

 

Om Prakash Yadav, Janaki Medical College

Department of Physiology

Vijay Kumar Sah, Janaki Medical College

Department of Medicine

Jitendra Kumar Singh, Janaki Medical College

Department of Community Medicine

Bharat Jha, Janaki Medical College

Professor, Biochemistry

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Published

2022-08-28

How to Cite

Prakash, S., Yadav, O. P., Sah, V. K., Singh, J. K., & Jha, B. (2022). Correlation of Biochemical Parameters among Diabetes patients attending Medicine OPD of Janaki Medical College Teaching Hospital. Janaki Medical College Journal of Medical Science, 10(2), 11–22. https://doi.org/10.3126/jmcjms.v10i2.47852

Issue

Section

Research Articles