Comparison of acute pressor effects of plain water, oral rehydration solution, and fruit juice ingestion in healthy young adults
DOI:
https://doi.org/10.3126/jmcjms.v7i1.30007Keywords:
fluid ingestion, fruit juice, oral rehydration solution, plain water, pressor effectAbstract
Background and Objectives: Ingestion of plain water is associated with an acute rise in blood pressure, probably due to elicitation of a sympathetic reflex in patients with autonomic dysfunction. Whether the pressor response is similar in healthy individuals is disputed. Other types of fluid could have different effects. Comparison of the pressor effects of plain water ingestion with other types of fluids has been reported scantily.
Material and methods: In a cross-over experimental study, young medical students ingested 500 mL of plain water (PW), 500 mL of oral rehydration salt solution (ORS), or 400 mL of commercial fruit juice (FJ) on separate days, with at least two days’ gap. Their heart rate (HR) and blood pressure (BP: systolic, SBP and diastolic, DBP) were recorded before, immediately after (0 min), and at 2, 5, 20, and 40 min after fluid ingestion and compared with baseline values.
Results: Sixty nine apparently healthy medical students (40 males and 29 females, age range 18-24 years) participated in the study. Compared to baseline, SBP and DBP were significantly higher at 0, 2, and 5 min measurements with ORS and FJ; then lowered at 20 and 40 min. With the PW, BP changes were not significant at any time of measurement. In all experimental set ups, HR increased significantly at 0, 2, and 5 min and lowered to near baseline levels then after.
Conclusion: Ingestion of ORS and FJ, but not PW, is associated with acute pressor effects in healthy young adults. This finding could have implications on the choice of fluid for prophylaxis in hypotensive conditions such as blood donation, postural hypotension, and autonomic dysfunction.
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2. Cariga P, Mathias CJ. Haemodynamics of the pressor effect of oral water in human sympathetic denervation due to autonomic failure. Clin Sci 2001;101:313–9.
3. Callegaro CC, Moraes RS, Negrão CE, Trombetta IC, Rondon MU, Teixeira MS, et al. Acute water ingestion increases arterial blood pressure in hypertensive and normotensive subjects. J Hum Hypertens 2007;21(7):564–70. DOI: 10.1038/sj.jhh.1002188
4. Mendonca G V, Teixeira MS, Heffernan KS, Fernhall B. Chronotropic and pressor effects of water ingestion at rest and in response to incremental dynamic exercise. Exp Physiol 2013;6:1133–43. DOI: 10.1113/expphysiol.2013.071886
5. Lu CC, Diedrich A, Tung CS, Paranjape SY, Harris PA, Byrne DW, et al. Water Ingestion as Prophylaxis Against Syncope. Circulation 2003;108(21):2660–5. DOI: 10.1161/01.CIR.0000101966.24899.CB
6. Berg K van den, Lam J, Bruhn R, Custer B, Murphy EL. Water administration and the risk of syncope and pressyncope during blood donation: a randomized clinical trial. Transfusion 2012;52:2577–84. DOI: 10.1111/j.1537-2995.2012.03631.x TRANSFUSION
7. Endo Y, Yamauchi K, Tsutsui Y, Ishihara Z, Yamazaki F, Sagawa S, et al. Changes in blood pressure and muscle sympathetic nerve activity during water drinking in humans. Jpn J Physiol 2002;52(5):421–7. DOI: 10.2170/jjphysiol.52.421
8. Jordan J, Shannon JR, Black BK, Ali Y, Farley M, Costa F, et al. The pressor response to water drinking in humans: a sympathetic reflex ? Circulation 2000;101:504–9. DOI: 10.1161/01.CIR.101.5.504
9. Routledge HC, Chowdhary S, Coote JH, Townend JN. Cardiac vagal response to water ingestion in normal human subjects. Clin Sci (Lond) 2002;103(2):157–62. DOI: 10.1042/CS20010317
10. Penggalih M, Gardjito M, Sofro Z. Banana isotonic drink improves orthostatic tolerance in voluntary dehydration subject. Int Food Res J 2012;19(3):883–7.
11. Figueroa JJ, Basford JR, Low PA. Preventing and treating orthostatic hypotension : as easy as A , B , C. Cleve Clin J Med 2010;77(5):298–306. DOI: 10.3949/ccjm.77a.09118
12. Peronnet F, Mignault D, Du Souich P, Vergne S, Bellego L Le, Jimenez L, et al. Pharmacokinetic analysis of absorption, distribution and disappearance of ingested water labeled with D2O in humans. Eur J Appl Physiol 2012;112(6):2213–22. DOI: 10.1007/s00421-011-2194-7
13. Bonk VA, France CR, Taylor BK. Distraction reduces self-reported physiological reactions to blood donation in novice donors with a blunting coping style. Psychosom Med 2001;63:447–52. PMID: 11382272
14. Pancheva M v, Pannchev VS, Suvandjieva A V. Improved orthostatic tolerance by leg crossing and muscle tensing : indisputable evidence for the arteriovenous pump existence. J Appl Physiol 2006;101(June 2006):1271–2. DOI: 10.1152/japplphysiol.00434.2006
15. Tank J, Schroeder C, Stoffels M, Diedrich A, Sharma AM, Luft FC, et al. Pressor effect of water drinking in tetraplegic patients may be a spinal reflex. Hypertension 2003;41(6):1234–9. DOI: 10.1161/01.HYP.0000070957.08219.C9
16. Sharma A, Gupta PK, Singh SN, Uprety D. Crystalloid prehydration versus cohydration for prevention of hypotension during spinal anaesthesia for elective caesarean section. Heal Renaiss 2014;12(3):190–6.
17. Scott EM, Greenwood JP, Gilbey SG, Stoker JB, Mary DASG. Water ingestion increases sympathetic vasoconstrictor discharge in normal human subjects. Clin Sci 2001 100:335–42.
18. Zdolsek J, Metander A, Hahn R. Volume kinetic evaluation of fluid turnover after oral intake of tap water, lemonade and saline in volunteers. BMC Sports Sci Med Rehabil 2016;8(1):1–7. DOI: 10.1186/s13102-016-0045-x
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