Effect of pre-anesthetic anxiety and heart rate on propofol dose requirement for induction: A correlation study

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DOI:

https://doi.org/10.3126/ajms.v8i2.15451

Keywords:

Anxiety, heart rate, propofol, induction

Abstract

Background: Though anxiety is associated with increase in heart rate and cardiac output, there is conflicting reports regarding its effect on propofol induction dose.

Aims and Objectives: The aim of the study was to delineate the correlation between pre-anesthetic anxiety and heart rate on propofol requirement for induction.

Materials and Methods: Total 42 patients of ASA (American Society of Anesthesiologists) physical status I and II, 13 male and 29 female, aged between 18 to 50 years and scheduled for elective surgery under general anesthesia, were enrolled in this study. Trait anxiety in the waiting room and state anxiety both in the waiting room and operating room were assessed using Spielberger’s revised State-Trait Anxiety Inventory (STAI) scale. After heart rate (HR) recording, anesthesia was induced with 200 ml/hr 1% propofol infusion till loss of verbal contact.

Results: Pre-anesthetic trait anxiety and HR had strong positive correlation with propofol requirement (ρ>0.6, P<0.05)while state anxiety had not. But pre-anesthetic state anxiety measured just before induction is strongly associated with increase in HR (ρ>0.6, P<0.05).

Conclusion: Pre-operative anxiety should be considered and the dose of propofol should be titrated for induction accordingly. Further, larger trials with more sophisticated monitoring are needed to confirm our findings.

Asian Journal of Medical Sciences Vol.8(2) 2017 64-68

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Author Biographies

Manjunatha SM, Bangalore Medical College and Research Institute, Bangalore 560002

Assistant Professor, Department of Anesthesiology

Rajdip Hazra, Nilratan Sircar Medical College and Hospital, Kolkata 700014

Tutor, Department of Anesthesiology

Ashok Das, ESIC Medical College and Hospital, Joka, Kolkata 700104

Assistant Professor, Department of Anesthesiology

Sisir Chakraborty, College of Medicine and Sagore Dutta Hospital, Kolkata 700058

Assistant Professor, Department of Medicine

Rajarshi Bose, Nilratan Sircar Medical College and Hospital, Kolkata 700014

Assistant Professor, Department of Pediatric Medicine

Swadesh Garain, Nadia District Hospital, Krisnanagar 741101

Specialist Medical Officer, Department of Gynecology and Obstetrics

Debaditya Purkait, Nilratan Sircar Medical College and Hospital, Kolkata 700014

Post-Graduate Trainee, Department of Anesthesiology

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Published

2017-03-01

How to Cite

SM, M., Hazra, R., Das, A., Chakraborty, S., Bose, R., Garain, S., & Purkait, D. (2017). Effect of pre-anesthetic anxiety and heart rate on propofol dose requirement for induction: A correlation study. Asian Journal of Medical Sciences, 8(2), 64–68. https://doi.org/10.3126/ajms.v8i2.15451

Issue

Vol. 8 No. 2 (2017)

Section

Original Articles

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