Comparison of Lipid Profile in Patients with Chronic Periodontitis and Patients with Healthy Periodontium

Authors

  • Shaili Pradhan Periodontology and Oral Implantology Unit, Department of Dental Surgery, Bir Hospital, National Academy of Medical Sciences, Mahabouddha, Kathmandu, Nepal
  • Rejina Shrestha Department of Dental Surgery, Kanti Children’s Hospital, National Academy of Medical Sciences, Maharajgunj, Kathmandu, Nepal
  • Ranjita Shrestha Gorkhali Periodontology and Oral Implantology Unit, Department of Dental Surgery, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal.
  • Pramod Kumar Koirala Periodontology and Oral Implantology Unit, Department of Dental Surgery, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal.
  • Suchana Adhikari Periodontology and Oral Implantology Unit, Department of Dental Surgery, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal.

DOI:

https://doi.org/10.3126/jnspoi.v6i1.52992

Keywords:

Cardiovascular disease, periodontitis, serum lipid profile

Abstract

Introduction: A positive relationship has been established between periodontal infections and cardiovascular diseases. Among various aetiological factors of cardiovascular diseases, hyperlipidaemia is a major cause. This study aims to compare the lipid profile in patients with chronic periodontitis and healthy periodontium.

Objective: The objective of the study was to compare the lipid profile in patients with periodontitis and healthy periodontium.

Methods: This analytical cross-sectional study was conducted from August 2020 to January 2021 among a total of 54 subjects recruited in the study who were divided into two groups: chronic periodontitis (CP) group (27 patients) and periodontally healthy group: 27 systemically healthy subjects with healthy periodontium. The periodontal parameters recorded were Plaque index (PI), Gingival index, Probing pocket depth, and Clinical attachment level. Serum levels of lipid profile were measured by enzymatic colorimetric method.

Results: The results showed that mean values of triglyceride and very low-density lipoprotein were higher in CP group than periodontally healthy group with significant difference. The mean value of high-density lipoprotein and low-density lipoprotein was lower in CP group than periodontally healthy group and the mean value of total cholesterol was higher in CP group than in periodontally healthy group with no significant difference.

Conclusions: Increased serum triglycerides was associated with chronic periodontitis. Chronic periodontitis may cause an increased risk for cardiovascular disease.

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Published

2022-06-30

How to Cite

Pradhan, S., Shrestha, R., Shrestha Gorkhali, R., Koirala, P. K., & Adhikari, S. (2022). Comparison of Lipid Profile in Patients with Chronic Periodontitis and Patients with Healthy Periodontium. Journal of Nepalese Society of Periodontology and Oral Implantology, 6(1), 3–7. https://doi.org/10.3126/jnspoi.v6i1.52992

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