Complete remission of nonmetastatic persistent gestational trophoblastic tumour by Methotrexate and Actinomycin D: A case report

Authors

  • Bashant Shah Department of Obstetrics and Gynecology, Paropakar Maternity and Women’s Hospital, Kathmandu
  • Ganesh Dangal Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu
  • Aruna Karki Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu
  • Hema Pradhan Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu
  • Ranjana Shrestha Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu
  • Kabin Bhattachan Department of Obstetrics and Gynecology, Kathmandu Model Hospital, Kathmandu

Keywords:

Persistent gestational trophoblastic tumour, molar pregnancy, Methotrexate

Abstract

Locally invasive non-metastatic persistent gestational trophoblastic tumours (PGTT) usually falls in low-risk group in WHO scoring system based on prognostic factors. We report a case of non-metastatic PGTT which followed a molar pregnancy. Complete remission of the tumour was achieved by 3 cycles of single agent chemotherapy (Methotrexate with leukovorin rescue) and 5 cycles of single agent (Actinomycin D).

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Published

2025-06-07

How to Cite

Shah, B., Dangal , G., Karki , A., Pradhan , H., Shrestha , R., & Bhattachan , K. (2025). Complete remission of nonmetastatic persistent gestational trophoblastic tumour by Methotrexate and Actinomycin D: A case report. Journal of Karnali Academy of Health Sciences, 8(1). Retrieved from https://nepjol.info/index.php/jkahs/article/view/85460

Issue

Vol. 8 No. 1 (2025): JKAHS; Jan - Aprl Issue(22)

Section

Case Reports

License

Copyright (c) 2025 Bashant Shah, Ganesh Dangal , Aruna Karki , Hema Pradhan , Ranjana Shrestha , Kabin Bhattachan

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.