Metabolic Bone Disease due to Renal Tubular Acidosis as a Primary Manifestation in a Patient with Sjogren’s Syndrome: A Case Report

Authors

  • A Bisht Department of Internal Medcine National Academy of Medical Sciences, Kathmandu, Nepal
  • PS Shrestha Department of Internal Medicine National Academy of Medical Sciences, Kathmandu, Nepal
  • D Mall Department of Internal Medicine National Academy of Medical Sciences, Kathmandu, Nepal
  • K Wasti Department of Internal Medcine National Academy of Medical Sciences, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/jdean.v8i3.65854

Keywords:

Metabolic bone disease, Renal Tubular Acidosis, Sjogren's Syndrome

Abstract

Background: Renal tubular acidosis (RTA) is a group of diseases where metabolic acidosis develops due to inability of renal tubules to maintain acid base balance despite normal glomerular filtration rate. Uncorrected acidosis in RTA can cause excess osteoclastic bone resorption and result in severe metabolic bone disease like rickets, osteomalacia and pathological fracture. Sjogren’s syndrome can cause distal RTA (type 1). Here, we report a case of a 35 years old female who presented with metabolic bone disease secondary to RTA resulting from Sjogren’s syndrome.

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Author Biographies

A Bisht, Department of Internal Medcine National Academy of Medical Sciences, Kathmandu, Nepal

Senior Resident, Diabetes and Endocrine Unit

PS Shrestha, Department of Internal Medicine National Academy of Medical Sciences, Kathmandu, Nepal

Consultant, Diabetes and Endocrine Unit

D Mall, Department of Internal Medicine National Academy of Medical Sciences, Kathmandu, Nepal

Assistant Professor, Diabetes and Endocrine Unit

K Wasti, Department of Internal Medcine National Academy of Medical Sciences, Kathmandu, Nepal

Senior Resident, Diabetes and Endocrine Unit

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Published

2024-05-14

How to Cite

Bisht, A., Shrestha, P., Mall, D., & Wasti, K. (2024). Metabolic Bone Disease due to Renal Tubular Acidosis as a Primary Manifestation in a Patient with Sjogren’s Syndrome: A Case Report. Journal of Diabetes and Endocrinology Association of Nepal, 8(3), 21–24. https://doi.org/10.3126/jdean.v8i3.65854

Issue

Section

Case Reports