Pyoderma Gangrenosum with Positive Antinuclear Antibody, in the Absence of Systemic Association

Authors

  • Smriti Shrestha Dhulikhel Hospital, Kathmandu University-Teaching Hospital, Dhulikhel, Kavre
  • Alisha Aryal Dhulikhel Hospital, Kathmandu University-Teaching Hospital, Dhulikhel, Kavre

Keywords:

Antibodies, connective tissue diseases, lupus erythematosus, vasculitis, leukocytoclastic

Abstract

Pyoderma gangrenosum is an uncommon neutrophilic dermatosis, seen on legs, and infrequently on hands and other anatomical sites. It is associated with systemic diseases in 50-70% of the cases. Antinuclear antibody (ANA) seropositivity has been reported in pyoderma gangrenosum associated with connective tissue disorders. However, there are very few case reports of pyoderma gangrenosum in patients of systemic lupus erythematosus, while we did not find any reports of ANA seropositivity in isolated pyoderma gangrenosum. Hence, we report this unique case of pyoderma gangrenosum with classical clinicohistopathology, positive ANA but no systemic association. As anticipated, our patient responded promptly to steroids.

Abstract
2397
PDF
25

Author Biographies

Smriti Shrestha, Dhulikhel Hospital, Kathmandu University-Teaching Hospital, Dhulikhel, Kavre

Lecturer, Department of Dermatology

Alisha Aryal, Dhulikhel Hospital, Kathmandu University-Teaching Hospital, Dhulikhel, Kavre

Second Year Resident, Department of Dermatology

Downloads

Published

2018-03-29

Issue

Vol. 16 No. 1 (2018)

Section

Case Reports

License

This license enables re-users to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.

How to Cite

Shrestha, S., & Aryal, A. (2018). Pyoderma Gangrenosum with Positive Antinuclear Antibody, in the Absence of Systemic Association. Nepal Journal of Dermatology, Venereology & Leprology, 16(1), 66-69. https://doi.org/10.3126/njdvl.v16i1.19418