Study of Antimicrobial Activity of ZnO Nanoparticles Dopped Natural Hydroxyapatites

Authors

  • Dirgha Raj Karki Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal
  • Sushant Bhujel Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal
  • Kshama Parajuli Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal
  • Ramesh Raj Pant Central Department of Environmental Science, Tribhuvan University, Kirtipur, Kathmandu, Nepal
  • Motee Lal Sharma Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/jncs.v44i1.62677

Keywords:

Bone waste, ZnO nanoparticles, Hydroxyapatite, Antimicrobial activity, Bone tissue engineering

Abstract

Bone replacements and repairs often encounter infections from diverse microbes, necessitating costly and painful secondary surgeries and treatments. Developing antimicrobial bone implants is crucial to mitigate these complications and enhance regeneration. Moreover, the biological synthesis of hydroxyapatite (Ca10(PO₄)6(OH)2, a primary component of human bone, presents advantages over chemically synthesized alternatives due to lower impurity and cost. This study focuses on synthesizing hydroxyapatite powders from buffalo and goat femoral bones, with the incorporation of ZnO nanoparticles. Analyzed via XRD and FTIR, the prepared powder exhibited potent antimicrobial properties against various bacterial strains. Specifically, the hydroxyapatite powder doped with ZnO nanoparticles displayed superior antimicrobial activity. Consequently, this synthesized material holds significant promise for applications in bone tissue engineering and related fields.

Downloads

Download data is not yet available.
Abstract
160
PDF
90

Downloads

Published

2024-02-21

How to Cite

Karki, D. R., Bhujel, S., Parajuli, K., Pant, R. R., & Sharma, M. L. (2024). Study of Antimicrobial Activity of ZnO Nanoparticles Dopped Natural Hydroxyapatites. Journal of Nepal Chemical Society, 44(1), 31–40. https://doi.org/10.3126/jncs.v44i1.62677

Issue

Section

Research Article