Effect of Dietary Intervention Using Low-Carbohydrate Diet to Manage Newly Diagnosed Type 2 Diabetes Mellitus in TUTH Hospital, Nepal

Authors

  • Aarem Karkee Patan Academy of Health Sciences, Lagankhel, Nepal https://orcid.org/0000-0002-9077-2834
  • Samir Singh KIST Medical College and Teaching Hospital, Imadole, Lalitpur, Nepal
  • Pradeep Krishna Shrestha Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Nani Shova Shakya Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Sadiksha Shrestha Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Samiksha Niroula College of Applied Food and Dairy Technology, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/nmj.v4i1.34710

Keywords:

Low-carbohydrate diet; HbA1c; Diabetes Mellitus

Abstract

Introduction: Low-carbohydrate diet is effective in improving blood glucose parameters, glycated hemoglobin A1c, weight, and waist circumference. The effectiveness of this diet is well accepted in America and the United Kingdom but in Nepal due to many preexisted misbeliefs regarding carbohydrates, we still have a carbohydrate-based diet for type 2 diabetes mellitus.
Material and Methods: Fifty-four newly diagnosed type 2 diabetes mellitus without any treatment were selected for solely low-carbohydrate diet intervention (<130g carbohydrate) in the endocrinology unit of Tribhuvan University Teaching Hospital, Kathmandu from March to August 2019. Antidiabetic medications were not used. Individualized diet plans and repeated counseling were given and followed for 3 months. Blood glucose (fasting and postprandial),
glycated hemoglobin A1c, weight, and waist circumference were compared at entry and 3 months. Statistical analysis was done using SPSS version 21.
Results: The mean ± SD age was 44.77 ± 10.32. The mean body weight decreased by 4.52 ± 1.79 kg (p<0.001), mean waist circumference decreased by 7.85±0.72 cm (p<0.001), mean fasting blood glucose decreased from 10.44±3.52 mmol/L to 6.18±1.02 mmol/L (p<0.001), mean postprandial blood glucose decreased from 16.76±8.26 mmol/L to 8.26±1.66 mmol/L (p<0.001) and mean glycated hemoglobin A1c decreased by 2.38 ± 1.49 % (p<0.001) after 3
months of low-carbohydrate diet intervention.
Conclusions: The use of a low-carbohydrate diet may effectively produce glycemic control and decrease glycated hemoglobin A1c without medication in newly diagnosed type 2 diabetes mellitus. Additionally, this diet may also help to lower weight and waist circumference in newly diagnosed type 2 diabetes mellitus.

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Author Biographies

Aarem Karkee, Patan Academy of Health Sciences, Lagankhel, Nepal

Nutrition and Dietetics

Samir Singh, KIST Medical College and Teaching Hospital, Imadole, Lalitpur, Nepal

Department of Biochemistry

Pradeep Krishna Shrestha, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Department of Internal Medicine

Nani Shova Shakya, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Department of Dietetics,

Sadiksha Shrestha, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Department of Biochemistry

Samiksha Niroula, College of Applied Food and Dairy Technology, Kathmandu, Nepal

Department of Nutrition and Dietetics

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Published

2021-06-30

How to Cite

Karkee, A., Singh, S., Shrestha, P. K. ., Shakya, N. S., Shrestha, S., & Niroula, S. (2021). Effect of Dietary Intervention Using Low-Carbohydrate Diet to Manage Newly Diagnosed Type 2 Diabetes Mellitus in TUTH Hospital, Nepal. Nepalese Medical Journal, 4(1), 419–423. https://doi.org/10.3126/nmj.v4i1.34710

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Original Articles