@article{Yadav_Bhaskar_Bajracharya_Sharma_Maharjan_Bhadeshwar_2022, title={Study of Glycated Haemoglobin and Lipid Profile in Type-2 Diabetes Mellitus}, volume={2}, url={https://nepjol.info/index.php/njhs/article/view/47157}, DOI={10.3126/njhs.v2i1.47157}, abstractNote={<p><strong>Introduction:</strong> Diabetes Mellitus is characterized by chronic hyperglycemia with disturbances of carbohydrate, fat, and protein metabolism resulting from defects in insulin secretion, insulin action, or both.</p> <p><strong>Objective:</strong> To compare the biochemical parameters which included glycated hemoglobin, serum total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol of people with diabetes mellitus and matched nondiabetic controls.</p> <p><strong>Methods:</strong> The cross-sectional hospital-based study was conducted among 60 diabetics and 30 nondiabetic patients. Fasting blood samples of 5 ml were collected from both the study sample and control sample. Biochemical parameters like glycated hemoglobin, serum total cholesterol, serum triglyceride, serum high-density lipoprotein cholesterol, and serum low-density lipoprotein cholesterol were analyzed with the help of a semi-automated analyzer, Erba Chem5, and Colorimeter-Systronic. Means of glycated hemoglobin, total cholesterol, triglyceride, high-density lipoprotein, and low-density lipoprotein were estimated<br />among the cases and controls. The student`s t-test was used to compare the mean values.</p> <p><strong>Results:</strong> A statistically significant difference was observed in mean glycated hemoglobin, total cholesterol, triglyceride, high density lipoprotein and low-density lipoprotein among the cases and controls (p-value<0.05).</p> <p><strong>Conclusions:</strong> This study concluded that there was a significant difference in mean glycated hemoglobin, total cholesterol, triglyceride, high-density cholesterol, and low-density cholesterol among the cases and controls. It is suggestive that lipid profile must be considered among diabetic patients which could be beneficial to prevent the risk of cardiovascular complications.</p>}, number={1}, journal={Nepal Journal of Health Sciences}, author={Yadav, Tapeshwar and Bhaskar, M. Vijaya and Bajracharya, Jayendra and Sharma, S. S. B. and Maharjan, Nikky and Bhadeshwar, Sushma}, year={2022}, month={Aug.}, pages={17–21} }