Serum Vitamin D Level in Patients Undergoing Coronary Artery Catheterization

Authors

  • Bikash Nepal B. P. Koirala Institute of Health Sciences, Dharan, Nepal https://orcid.org/0000-0001-8189-2466
  • Ajit Sah B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Biplave Karki B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Jeet Prasad Ghimire B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Aditya Mahaseth B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Swapnil Pandit B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Ajit Sah B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Surendra Uranw B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Naveen Kumar Pandey B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Prashant Shah B. P. Koirala Institute of Health Sciences, Dharan, Nepal
  • Prahlad Karki B. P. Koirala Institute of Health Sciences, Dharan, Nepal

DOI:

https://doi.org/10.3126/jbpkihs.v4i1.37234

Keywords:

Coronary angiography, Coronary artery disease, Vitamin D deficiency

Abstract

Background: Vitamin D deficiency may be a risk factor for coronary artery disease (CAD). We aimed to measure the prevalence of vitamin D deficiency in CAD and its association with severity of angiographic proven CAD.

Methods: This prospective, cross-sectional study included 106 consecutive patients who were admitted for typical angina and had signs of myocardial injury (ECG findings and/ or elevated troponin I or CK-MB) and who underwent coronary angiography at the university hospital of BPKIHS from August 2020 to April 2021. Patients were categorized into angiographic proven CAD group and angiographic normal coronary artery group. Serum vitamin D level was classified as normal (≥ 30 ng/ml) and deficiency (< 30 ng/ml).

Results: Out of 106 patients, 78 patients (73.6%) had vitamin D deficiency and 28 (26.4%) had normal vitamin D level (p = 0.39). Vitamin D level (mean ± SD) in patients with angiographic normal coronary artery and angiographic proven CAD were 25.94 ± 11.63 ng/ml and 26.07 ± 12.90 ng/ml respectively (p = 0.97). Prevalence of vitamin D deficiency was 75.0% and 64.3% in significant CAD group and normal coronary artery group respectively (p = 0.39). Similarly, frequency of vitamin D deficiency were 68.6%, 78.3% and 88.90% in single, double, and triple vessel disease respectively (p = 0.21). The vitamin D level (mean ± SD) in single, double and triple vessel disease were 27.31 ± 14.02 ng/ml, 25.69 ± 12.72 ng/ml, 23.08 ± 9.45 ng/ml respectively.

Conclusion: The prevalence of vitamin D deficiency in both angiographic normal coronary artery and angiographic proven CAD were high but comparable. There was no association of vitamin D deficiency with severity of angiographic proven CAD.

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Author Biographies

Bikash Nepal, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Ajit Sah, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Biplave Karki, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Jeet Prasad Ghimire, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Aditya Mahaseth, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Swapnil Pandit, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Ajit Sah, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Surendra Uranw, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Internal Medicine

Naveen Kumar Pandey, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Prashant Shah, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

Prahlad Karki, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Department of Cardiology

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Published

2021-06-30

How to Cite

Nepal, B., Sah, A., Karki, B., Ghimire, J. P., Mahaseth, A., Pandit, S., Sah, A., Uranw, S., Pandey, N. K., Shah, P., & Karki, P. (2021). Serum Vitamin D Level in Patients Undergoing Coronary Artery Catheterization. Journal of BP Koirala Institute of Health Sciences, 4(1), 9–14. https://doi.org/10.3126/jbpkihs.v4i1.37234

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Original Articles