Acanthamoeba Keratitis- Camouflage Entity in Eastern Nepal: A Case Series

Authors

DOI:

https://doi.org/10.3126/jbpkihs.v4i1.37071

Keywords:

Acanthamoeba keratitis, Cornea, Nepal, Polymerase Chain Reaction

Abstract

Acanthamoeba keratitis is a sight-threatening corneal infection and is a growing clinical problem in the world. Though Acanthamoeba keratitis is considered uncommon and rarely reported in Nepal, we encountered six cases in 2019. All patients had redness, photophobia, decreased vision, and pain with ring infiltrate. Ten percent potassium hydroxide mount revealed Acanthamoeba cyst in all cases. Non-nutrient agar overladen with Escherichia coli revealed feeding tracks and Polymerase Chain Reaction revealed T4 genotype Acanthamoeba in four cases. Amoebicidal treatment was started with chlorhexidine 0.02% eye drop half-hourly and supplementary treatment included moxifloxacin eye drop, a combination of polymyxin B sulfate, neomycin sulfate, and bacitracin eye ointment. After treatment, one patient had the best-corrected visual acuity of 6/9 while others had a visual outcome of hand movement. A high level of clinical suspicion and wet mount examination of specimen from infected corneal tissue are essential to aid in rapid diagnosis.

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Author Biographies

Sanjay Kumar Singh, Biratnagar Eye Hospital, Biratnagar, Nepal

Department of Cornea

Karthik Ambur, Biratnagar Eye Hospital, Biratnagar, Nepal

   

Prija Poudyal, Biratnagar Eye Hospital, Biratnagar, Nepal

Department of Ophthalmic Pathology and Laboratory Medicine

Sagun Malla, Biratnagar Eye Hospital, Biratnagar, Nepal

    

Amit Rajbanshi, Biratnagar Eye Hospital, Biratnagar, Nepal

Department of Ophthalmic Pathology and Laboratory Medicine

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Published

2021-06-30

How to Cite

Singh, S. K., Ambur, K., Poudyal, P., Malla, S., & Rajbanshi, A. (2021). Acanthamoeba Keratitis- Camouflage Entity in Eastern Nepal: A Case Series. Journal of BP Koirala Institute of Health Sciences, 4(1), 59–63. https://doi.org/10.3126/jbpkihs.v4i1.37071

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Section

Case Reports