Pantoprazole Induced Thrombocytopenia: a Case report

Authors

  • Deebya Raj Mishra Department of Internal Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal
  • K. Dahal Department of Internal Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal
  • P.P. Gupta Department of General Practice and Emergency Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal

DOI:

https://doi.org/10.3126/jbpkihs.v1i2.22088

Keywords:

Pantoprazole, Thrombocytopenia

Abstract

Proton Pump Inhibitors serve as the cornerstone of management of Upper Gastrointestinal bleeding. In Nepal, intravenous Pantoprazole is widely used. One of the rare complications of intravenous Pantoprazole is thrombocytopenia which may lead to paradoxical increase in bleeding possibility. Here, we present a 70 year old gentleman who presented with hematemesis and melena and was treated with IV Pantoprazole. The Platelet count started decreasing from the third day onwards following which the patient was switched to Rabeprazole on the fourth day. Platelet count subsequently normalized. Thus, drug induced thrombocytopenia is one of the rare complications that has to be kept in mind with the use of Pantoprazole.

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Published

2018-12-21

How to Cite

Mishra, D. R., Dahal, K., & Gupta, P. (2018). Pantoprazole Induced Thrombocytopenia: a Case report. Journal of BP Koirala Institute of Health Sciences, 1(2), 105–107. https://doi.org/10.3126/jbpkihs.v1i2.22088

Issue

Vol. 1 No. 2 (2018)

Section

Case Reports

License

This license enables reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.