Synthesis and Characterization of Copper Oxide Nanoparticles Isolated from Acmella oleracea and Study of Antimicrobial and Phytochemical Properties

Authors

  • Sujan Dhungana Department of Chemistry, Tri Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
  • Anusa Gauli Department of Chemistry, Tri Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
  • Laxmi Tiwari Department of Chemistry, Tri Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
  • Devendra Khadka Tribhuvan Multiple Campus, Tansen, Palpa, Nepal
  • Surendra Kumar Gautam Department of Chemistry, Tri Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
  • Megh Raj Pokhrel Central Department of Chemistry, Kirtipur, Kathmandu, Nepal
  • Janaki Baral Department of Chemistry, Tri Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
  • Bhoj Raj Poudel Department of Chemistry, Tri Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/arj.v5i1.73521

Keywords:

Acmella oleracea, green synthesis, nanoparticles, antimicrobial, phytochemicals

Abstract

This study utilized a green synthesis approach to produce CuO nanoparticles employing flower extract of Acmella oleracea where plant-derived biomolecules served as natural reducing and stabilizing agents. The synthesized nanoparticles were characterized through X-ray diffraction (XRD), UV-Vis spectroscopy, and Fourier Transform Infrared (FTIR) analysis. XRD suggested the monoclinic phase of nanoparticles that belong to the C2/c space group with a crystallite size of 17.35 nm on average. The band gap was calculated using the Tauc model which was 2.27 eV. Phytochemical screening confirmed the presence of alkaloids, essential for nanoparticle formation, through Mayer’s, Dragendorff’s, Wagner’s, and Hager’s tests. Antimicrobial tests showed that the CuO nanoparticles had significant activity against microbes such as Escherichia coli, Staphylococcus aureus, and Candida albicans, with inhibition zones of 1.5 to 1.8 cm. These findings highlight the potential of Acmella oleracea mediated CuO nanoparticles for biomedical and environmental applications.

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Published

2024-12-31

How to Cite

Dhungana, S., Gauli, A., Tiwari, L., Khadka, D., Gautam, S. K., Pokhrel, M. R., … Poudel, B. R. (2024). Synthesis and Characterization of Copper Oxide Nanoparticles Isolated from Acmella oleracea and Study of Antimicrobial and Phytochemical Properties. Amrit Research Journal, 5(1), 18–29. https://doi.org/10.3126/arj.v5i1.73521

Issue

Vol. 5 No. 1 (2024)

Section

Articles