Green Synthesis and Characterization of Copper-Zinc Alloy Nanoparticles Using Stem Extract of Tinospora cordifolia and Comparative Study of Anti-Microbial Properties

Authors

  • Anup Subedee Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Sita Shrestha Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Sabita Ghimire Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Ishwor Pathak Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Hari Bhakta Oli Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Arun Kumar Sharma Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Bishma Raj Pandey Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Puspa Lal Homagai Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Ram Lal Shrestha Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Deval Prasad Bhattarai Amrit Campus, Tribhuvan University, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/amritj.v3i1.61544

Keywords:

Tinospora cordifolia, green synthesis, CU NPs, Zn NPs, Cu-Zn NPs

Abstract

Bimetallic nanoparticles are prepared from the combination of two different metals in a certain ratio and are getting importance over monometallic nanoparticles due to their better properties. In this work, copper-zinc nanoparticles (Cu-Zn NPs) have been prepared by reducing the metal precursors using Tinospora cordifolia (Gurjo) stem extract as a reducing, capping, and stabilizing agent. The physicochemical properties of bimetallic nanoparticles have been studied in terms of UV-vis spectra, XRD and FTIR. Biological activities of as-synthesized nanoparticles were tested against Bacillus subtilis, Escherichia coli, and Candida albicans. The Cu-Zn NPs exhibited remarkable antibacterial as well as antifungal activities compared to either nanoparticle alone. Based on the findings, it can be revealed that Cu-Zn NPs can serve as good antimicrobial agent.

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Published

2023-12-31

How to Cite

Subedee, A., Shrestha, S., Ghimire, S., Pathak, I., Oli, H. B., Sharma, A. K., Pandey, B. R., Homagai, P. L., Shrestha, R. L., & Bhattarai, D. P. (2023). Green Synthesis and Characterization of Copper-Zinc Alloy Nanoparticles Using Stem Extract of Tinospora cordifolia and Comparative Study of Anti-Microbial Properties. Amrit Journal, 3(1), 78–90. https://doi.org/10.3126/amritj.v3i1.61544

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Articles