Green Synthesis and Characterization of Copper-Zinc Alloy Nanoparticles Using Stem Extract of Tinospora cordifolia and Comparative Study of Anti-Microbial Properties

Authors

  • Anup Subedee Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Sita Shrestha Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Sabita Ghimire Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Ishwor Pathak Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Hari Bhakta Oli Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Arun Kumar Sharma Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Bishma Raj Pandey Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Puspa Lal Homagai Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Ram Lal Shrestha Amrit Campus, Tribhuvan University, Kathmandu, Nepal
  • Deval Prasad Bhattarai Amrit Campus, Tribhuvan University, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/amritj.v3i1.61544

Keywords:

Tinospora cordifolia, green synthesis, CU NPs, Zn NPs, Cu-Zn NPs

Abstract

Bimetallic nanoparticles are prepared from the combination of two different metals in a certain ratio and are getting importance over monometallic nanoparticles due to their better properties. In this work, copper-zinc nanoparticles (Cu-Zn NPs) have been prepared by reducing the metal precursors using Tinospora cordifolia (Gurjo) stem extract as a reducing, capping, and stabilizing agent. The physicochemical properties of bimetallic nanoparticles have been studied in terms of UV-vis spectra, XRD and FTIR. Biological activities of as-synthesized nanoparticles were tested against Bacillus subtilis, Escherichia coli, and Candida albicans. The Cu-Zn NPs exhibited remarkable antibacterial as well as antifungal activities compared to either nanoparticle alone. Based on the findings, it can be revealed that Cu-Zn NPs can serve as good antimicrobial agent.

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Published

2023-12-31

How to Cite

Subedee, A., Shrestha, S., Ghimire, S., Pathak, I., Oli, H. B., Sharma, A. K., Pandey, B. R., Homagai, P. L., Shrestha, R. L., & Bhattarai, D. P. (2023). Green Synthesis and Characterization of Copper-Zinc Alloy Nanoparticles Using Stem Extract of Tinospora cordifolia and Comparative Study of Anti-Microbial Properties. Amrit Journal, 3(1), 78–90. https://doi.org/10.3126/amritj.v3i1.61544

Issue

Vol. 3 No. 1 (2023)

Section

Articles

License

Copyright (c) 2023 Anup Subedee, Sita Shrestha, Sabita Ghimire, Ishwor Pathak, Hari Bhakta Oli, Arun Kumar Sharma, Bishma Raj Pandey, Puspa Lal Homagai, Ram Lal Shrestha, Deval Prasad Bhattarai

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