Lewandowski & Lutz Syndrome: A Rare Case Entity

Abstract

Epidermodysplasia verruciformis (EV), first described in 1922 by Lewandowski and Lutz, is a rare inherited genetic disease. The disease usually manifests in childhood with highly polymorphic, widespread lesions.

We report a case of a fifteen year old boy, who presented to us with multiple flat topped, hypopigmented papules of a seven year duration on his body. He was diagnosed with EV on a skin biopsy, after ruling out differential diagnosis of pityriasis versicolor, verruca vulgaris and acrokeratosisverruciformis. The patient was resistant to known treatment options.

Key message: sun protection and lifelong observation for diagnosis and improved prognosis of malignant or premalignant lesions of EV.