Study of Clinical Profiles, Risk Factors and Coronary Angiographic Patterns in Female Patients Presenting with Anginal Chest Pain in a Tertiary Care Centre of Nepal

Authors

  • Suman Adhikari Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Ratna Mani Gajurel Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Chandra Mani Poudel Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Hemant Shrestha Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Sanjeev Thapa Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Surya Devkota Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Bhawani Manandhar Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Rajaram Khanal Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Smriti Shakya Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Vijay Yadav Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Manju Sharma Department of Cardiology, Manmohan Cardiothoracic and Vascular Transplant Centre, Tribhuvan University, Institute of Medicine, Kathmandu, 44600, Nepal.
  • Ravi Sahi Department of Cardiology, Shahid Gangalal National Heart Centre, Kathmandu, Nepal.
  • Jeevan Thapa Patan Academy of Health Sciences, Lalitpur, Nepal

DOI:

https://doi.org/10.3126/njh.v20i2.48868

Keywords:

Angina, Females, Ischemic heart disease, Risk factors.

Abstract

Background and Aims: Coronary artery disease is one of the important causes of deaths in females in many countries. Females with chest pain are more likely to be treated in a different way as compared to males at the time of presentation. Worldwide, there has been a considerable rise in the number of females who are undergoing coronary angiography recently.

Methods: This study was a single-centre, prospective, observational study conducted in the department of cardiology, MCVTC, Tribhuvan University, Nepal. The study period was from 5th  July 2020 to  4th July 2021.155 female patients with anginal chest pain were enrolled. Data were collected after thorough history taking, physical examination, laboratory investigations, and coronary angiography. They were further divided into three age groups:<50 years,50-65 years and >65 years. Subsequently statistical analysis was done using latest version of SPSS.

Results: The mean age of the patients was 59.64 years (SD=11.428). There were 119 (76.77%) postmenopausal patients. The most prevalent risk factor of IHD  was HTN (43.87% ). Obesity/overweight was most common (58.62%) in those with age <50 years. DM was most common (26.32%) in age group 50-65 years. HTN was the most prevalent (52.63%) in age group 50-65 years. The maximum proportion of dyslipidemic patients (34.21%) were found in age group 50-65 years. 52.25% patients presented with acute coronary syndrome. 33.55% patients had normal coronary arteries. 11.61% patients had nonobstructive coronary artery disease.

Obstructive coronary artery disease was found in 51.61% patients. IN patients with obstructive CAD, LAD was the most commonly involved vessel followed by RCA .

Conclusion: Findings from our study shows higher prevalence of risk factors for IHD in Nepalese females. This study also demonstrates that as females get older and become postmenopausal, the number of risk factors for CAD increases. Understanding the risk factors for CAD and angiographic patterns in females could be helpful in implementing optimal treatment strategies in females with angina.

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Published

2022-11-21

How to Cite

Adhikari, S., Gajurel, R. M., Poudel, C. M., Shrestha, H., Thapa, S., Devkota, S., Manandhar, B., Khanal, R., Shakya, S., Yadav, V., Sharma, M., Sahi, R., & Thapa, J. (2022). Study of Clinical Profiles, Risk Factors and Coronary Angiographic Patterns in Female Patients Presenting with Anginal Chest Pain in a Tertiary Care Centre of Nepal. Nepalese Heart Journal, 19(2), 13–18. https://doi.org/10.3126/njh.v20i2.48868

Issue

Vol. 19 No. 2 (2022)

Section

Original Articles

License

Copyright (c) 2022 Nepalese Heart Journal

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