Bleb-related Infection following Trabeculectomy

Authors

  • Madhu Thapa B.P. Koirala Lions Centre of Ophthalmic Studies, Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Kathmandu, Nepal https://orcid.org/0000-0001-6697-6258
  • Pragati Gautam
  • Sareena Pachai B.P. Koirala Lions Centre of Ophthalmic Studies, Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/nepjoph.v17i1.69157

Keywords:

Antimetabolites, avascular bleb, bleb-related endophthalmitis, trabeculectomy.

Abstract

Introduction: Bleb-related endophthalmitis after trabeculectomy is a rare but sight threatening complication. Thin walled blebs, occurring after adjunctive use of antimetabolite like mitomycin C and 5-flurouracil, is an important risk factor for bleb-related infections.

Case: Forty-five years old one-eyed male had undergone trabeculectomy in past, had presented with diminution of vision, pain, photophobia in his seeing eye.

Observation: On examination, best corrected visual acuity was 5/60, thin walled avascular bleb with congested conjunctiva, minimal hypopyon, pupil had fibrinous exudate and vitreous reaction. He was diagnosed as bleb-related endophthalmitis. He improved after intra-vitreal and topical antibiotics

Conclusion: Bleb-related infections can be controlled if diagnosed and treated on time.

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Published

2025-11-13

How to Cite

Thapa, M., Gautam, P., & Pachai, S. (2025). Bleb-related Infection following Trabeculectomy. Nepalese Journal of Ophthalmology, 17(1), 66–71. https://doi.org/10.3126/nepjoph.v17i1.69157