Efficacy of single dose of 800μg of misoprostol in first trimester abortion

Authors

  • Shanti Subedi Lecturer, Department of Gynaecology and Obstetrics, Nobel Medical College and Teaching Hospital, Biratnagar

DOI:

https://doi.org/10.3126/jonmc.v1i2.7293

Keywords:

Misoprostol, abortion, uterine curettage

Abstract

Objective: To assess the efficacy, safety and cost effectiveness of Misoprostol (Prostaglandin E1 analogue) as a single dose of 800?g in first trimester abortion

Methods: A descriptive study was conducted in Nobel Medical College and Teaching Hospital from June 2010-June 2011 where 110 patients were enrolled for first trimester abortions including incomplete, missed, blighted ovum. Each woman received a single dose of 800?g of Misoprostol intravaginally and the the process of abortion was monitored to assess the outcome measures.

Results: Successful abortion was seen in 102 patients (92.7%) with induction to delivery interval of < 24 hours and the remaining 8 (7.2%) of them had to undergo surgical evacuation. Side effects noted were lower abdominal pain, fever, nausea, vomiting, and diarrhoea. Mean hospital stay of the patients was 48 hours.

Conclusion: Misoprostol is a safe, cost effective and efficacious drug for first trimester abortion even as a single dosage.

DOI: http://dx.doi.org/10.3126/jonmc.v1i2.7293

Journal of Nobel Medical College (2012), Vol.1 No.2 p.11-13

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Published

2012-12-29

How to Cite

Subedi, S. (2012). Efficacy of single dose of 800&mu;g of misoprostol in first trimester abortion. Journal of Nobel Medical College, 1(2), 11–13. https://doi.org/10.3126/jonmc.v1i2.7293

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Section

Original Articles