Evaluation of Calcium Hydroxide, Triple Antibiotic Paste, Mineral Trioxide Aggregate and Biodentine as Pulp Capping Agents in Deep Carious Teeth

Authors

  • Sujan Thapa Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
  • Snigdha Shubham Universal College of Medical Sciences, Bhairahawa, Nepal
  • Vanita Gautam Universal College of Medical Sciences, Bhairahawa, Nepal
  • Manisha Nepal Kathmandu University School of Medical Sciences, Dhulikhel, Nepal
  • Rupam Tripathi Pokhara Academy of Health Sciences, Pokhara, Nepal

DOI:

https://doi.org/10.3126/jucms.v13i02.83851

Keywords:

Biodentine, Calcium Hydroxide, MTA, Pulp Capping, Triple Antibiotic Paste

Abstract

INTRODUCTION

Deep caries Management (DCM) with a reliable biomaterial is considered an alternative to Root Canal Treatment (RCT) provided the pulp is vital. Calcium Hydroxide (CH) and Mineral Trioxide Aggregate (MTA) are relatively more popular as pulp capping agents. Triple Antibiotic Paste (TAP) has been proposed for lesion sterilization and tissue repair (LSTR). Biodentine is relatively new biomaterial currently explored for vital pulp therapy.

MATERIAL AND METHODS

A total of 100 cases confirmed eligible for pulp capping were randomly assigned to either CH, TAP, MTA or Biodentine group (25 teeth per group). The allocated pulp capping agent was applied followed by Glass Ionomer Cement. Permanent restoration was done with composite at 3rd week. Clinical and radiographic evaluations were performed at 3 weeks, 3 months, 6 months and 1 year. Teeth presenting with severe pain or no response to pulp sensibility tests or demonstrating periapical changes in the radiograph were considered failures.

RESULTS

Biodentine and MTA had 22 (31.9%) successful cases each. CH had 13 (18.8%) successful cases and TAP had 12 (17.4%). There was statistically significant difference in the pain score between Biodentine and CH, between Biodentine and TAP at 6 months. There was statistically significant difference in the vitality of the teeth for the pulp capping materials at 3 weeks while no significant difference in the radiographic findings.

CONCLUSION

Biodentine and MTA showed better outcome than CH and TAP based on subjective symptoms, pulp sensibility tests and radiographic findings. Thus, Biodentine and MTA can be used as replacement for CH and TAP as pulp capping material.

 

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Author Biographies

Sujan Thapa, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal

Department of Dental

Snigdha Shubham, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Conservative Dentistry and Endodontics

Vanita Gautam, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Conservative Dentistry and Endodontics

Manisha Nepal, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal

Department of Conservative Dentistry and Endodontics

Rupam Tripathi, Pokhara Academy of Health Sciences, Pokhara, Nepal

Department of Conservative Dentistry and Endodontics

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Published

2025-09-10

How to Cite

Sujan Thapa, Snigdha Shubham, Vanita Gautam, Manisha Nepal, & Rupam Tripathi. (2025). Evaluation of Calcium Hydroxide, Triple Antibiotic Paste, Mineral Trioxide Aggregate and Biodentine as Pulp Capping Agents in Deep Carious Teeth. Journal of Universal College of Medical Sciences, 13(02), 31–36. https://doi.org/10.3126/jucms.v13i02.83851

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Section

Original Articles