Preoperative serum albumin level as a predictor of perioperative outcome in patient undergoing major gastrointestinal surgery

Authors

  • Tika Ram Bhandari Universal College of Medical Sciences, Bhairahawa, Nepal
  • Sudha Shahi National Academy of Medical Sciences, Kathmandu , Nepal
  • Ramesh Singh Bhandari Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
  • Paleswan Joshi Lakhey Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/jssn.v19i2.24544

Keywords:

Gastrointestinal Surgery, Hypoalbuminemia, Postoperative complication

Abstract

Introduction: Hypoalbuminemia, as a marker of malnutrition and disease, is associated with higher risk of poor postoperative outcomes. However, no study has been reported from our country until now. Our aim was to identify the relationship between preoperative hypoalbuminemia and the development of complications after major gastrointestinal surgery.

Methods: A prospective study of 106 patients who underwent major elective gastrointestinal surgery between July 2012 to June 2013 in Department of Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal were considered for the study. Serum albumin was determined preoperatively in all patients. Hypoalbuminemia was defined as albumin less than 35 mg/dl. Thirty-day postoperative complications were analyzed.

Results: The patients were 70 males (66 %) and 36 females (34%) with a mean age of 50 years (23-81). Thirty-six patients (34%) had hypoalbuminemia. Overall complication rate was 32%. Hypoalbuminemic patients had a significantly higher rate of postoperative complications (26.4 and 5.6%; P<0.05). In multivariate analysis, age (>50 year), BMI (<18 kg/m2), duration of surgery (>3 hours) and hypoalbuminemia (<35 mg/dl) were the significant risk factors for postoperative complications (P<0.05).

Conclusion: Preoperative hypoalbuminemia is an independent predictor of postoperative outcomes in patients with elective major gastrointestinal surgery. Identification and optimization of nutritional status prior to surgery may improve surgical outcomes.  

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Author Biographies

Tika Ram Bhandari, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of General Surgery

Sudha Shahi, National Academy of Medical Sciences, Kathmandu , Nepal

Department of ENT

Ramesh Singh Bhandari, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Department of Surgical Gastroenterology

Paleswan Joshi Lakhey, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Department of Surgical Gastroenterology

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Published

2016-12-31

How to Cite

Bhandari, T. R., Shahi, S., Bhandari, R. S., & Lakhey, P. J. (2016). Preoperative serum albumin level as a predictor of perioperative outcome in patient undergoing major gastrointestinal surgery. Journal of Society of Surgeons of Nepal, 19(2), 13–20. https://doi.org/10.3126/jssn.v19i2.24544

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Section

Original Articles