Intrathecal Magnesium Sulfate as Analgesic and Anaesthetic Adjunct to Bupivacaine in Patients Undergoing Lower Extremity Orthopaedic Surgery

Authors

  • Prakash Maden Limbu Department of Anaesthesiolgy & Critical Care Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan
  • Sindhu Khatiwada Department of Anaesthesiolgy & Critical Care Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan
  • Birendra Prasad Sah Department of Anaesthesiolgy & Critical Care Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan
  • Satyendra Narayan Singh Department of Anaesthesiolgy & Critical Care Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan
  • Krishna Pokharel Department of Anaesthesiolgy & Critical Care Medicine, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan
  • Rajiv Maharjan Department of Orthopaedics, B.P. Koirala Institute of Health Sciences, Buddha Road, Dharan

DOI:

https://doi.org/10.3126/jsan.v4i2.21207

Keywords:

Bupivacaine, Intrathecal Magnesium Sulfate, Spinal Anaesthesia

Abstract

Background: Subarachnoid block is a popular mode of anesthesia for lower limb surgeries. Studies of Magnesium Sulfate (MgS04 ) as an adjuvant to intrathecal local anaesthetic are limited. The objective was to find out the analgesic and anaesthetic effect of intrathecal MgS04 added to bupivacaine for spinal anaesthesia in patients undergoing lower extremity orthopaedic surgery.

Methods: Sixty ASA I or II adult patients undergoing lower extremity orthopaedic surgery were randomly allocated in a double blinded fashion into two groups of thirty each. Group A received 3.0 ml of 0.5% hyperbaric bupivacaine with 0.15 ml of 50% MgSO4. Group B received 3.0 ml of 0.5% hyperbaric bupivacaine with 0.15 ml of NS. Onset of sensory and motor block as well as time to attain highest level of sensory block were recorded. Duration of sensory and motor block along with duration of spinal anaesthesia were also assessed. Any adverse effects were noted and treated.

Results: Duration of sensory and motor block along with duration of spinal anaesthesia were prolonged in patients of MgSO4 but were not statistically significant with p-value of 0.33, 0.23 and 0.68 respectively. Onset of anaesthesia, requirement of rescue analgesics, haemodynamic parameters and adverse effects were comparable between two groups.

Conclusion: In patients undergoing lower extremity orthopaedic surgery the addition of 75mg of MgSO4 to intrathecal bupivacaine did not prolong the duration of sensory block, spinal anaesthesia nor decreased postoperative analgesic consumption without any additional side effects.

 Journal of Society of Anesthesiologists of Nepal

Vol. 4, No. 2, 2017, Page: 74-80

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Published

2018-10-01

How to Cite

Limbu, P. M., Khatiwada, S., Sah, B. P., Singh, S. N., Pokharel, K., & Maharjan, R. (2018). Intrathecal Magnesium Sulfate as Analgesic and Anaesthetic Adjunct to Bupivacaine in Patients Undergoing Lower Extremity Orthopaedic Surgery. Journal of Society of Anesthesiologists of Nepal, 4(2), 74–80. https://doi.org/10.3126/jsan.v4i2.21207

Issue

Vol. 4 No. 2 (2017)

Section

Original Articles

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