Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report

Authors

  • Swechha Maskey Nepal cancer hospital and research center https://orcid.org/0000-0002-4641-4183
  • Kapendra Shekhar Amatya Nepal Cancer Hospital and Research Center
  • Banita Gurung Nepal Cancer Hospital and Research Center
  • Suniti Shrestha Nepal Cancer Hospital and Research Center
  • Moushami Singh Nepal Cancer Hospital and Research Center
  • Shivani Sharma Core Diagnostics, Gurgaon, India
  • Hari Prasad Dhakal Nepal Cancer Hospital and Research Center

DOI:

https://doi.org/10.3126/jpn.v11i1.31629

Keywords:

Male breast; Metastasis; Urothelial carcinoma;

Abstract

Metastasis to the male breast is rarer than that of the female breast. Primary tumors of the urinary bladder to metastasize to the breast is more uncommon than other sites like lungs, ovary, or stomach. We report a case of a 59-year-old male patient with proven high-grade urothelial carcinoma of the bladder with lungs and anterior abdominal metastasis, presented with ulceroproliferative mass in the left breast nipple-areolar complex. Wide local excision was done and was sent for histopathological examination which showed neoplastic cells, morphologically resembling urothelial carcinoma. Immunohistochemical staining showed tumor cells positive for CK5/6, p63, GATA3, and Uroplankin, which confirmed the diagnosis and demonstrated the urothelial origin. There are no such cases reported to date in Nepal and very few cases are reported worldwide. Diagnostic accuracy depends on histologic analysis. Distinguishing between metastasis to the breast and primary breast tumor is important for therapy and prognosis.

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Author Biographies

Swechha Maskey, Nepal cancer hospital and research center

Department of Pathology and Laboratory Medicine,Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal

Kapendra Shekhar Amatya, Nepal Cancer Hospital and Research Center

Department of Surgical Oncology, Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal

Banita Gurung, Nepal Cancer Hospital and Research Center

Department of Pathology and Laboratory Medicine,Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal

Suniti Shrestha, Nepal Cancer Hospital and Research Center

Department of Pathology and Laboratory Medicine,Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal

Moushami Singh, Nepal Cancer Hospital and Research Center

Department of Pathology and Laboratory Medicine,Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal

Shivani Sharma, Core Diagnostics, Gurgaon, India

Core Diagnostics, Gurgaon, India

Hari Prasad Dhakal, Nepal Cancer Hospital and Research Center

Department of Pathology and Laboratory Medicine,Nepal Cancer Hospital and Research Center, Harisiddhi, Lalitpur, Nepal

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Published

2021-09-30

How to Cite

Maskey, S., Amatya, K. S., Gurung, B., Shrestha, S., Singh, M., Sharma, S., & Dhakal, H. P. (2021). Metastasis to the male breast from carcinoma of the urinary bladder: a rare case report. Journal of Pathology of Nepal, 11(2), 1870–1872. https://doi.org/10.3126/jpn.v11i1.31629

Issue

Section

Case Reports

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