Management Issues of HIV Infection in Poor Resource Setting Due to Unavailability of Drug Sensitivity Testing
DOI:
https://doi.org/10.3126/jnps.v33i2.7699Keywords:
Drug sensitivity testing, HIV Treatment failure, Health resource poor settingAbstract
Despite the obvious benefits that rapid scale-up of antiretroviral therapy (ART) has had on cases of human immunodeficiency virus (HIV), treatment failure that is mostly associated with the emergence of HIV drug resistance still remains a major challenge. Index case is a stage 4 HIV patient who failed multiple ART, including nucleoside and nonnucleoside reverse transcriptase inhibitors (NRTIs and NNRTIs) and protease inhibitors (PIs). His clinical and immunological markers continued to fail despite completion of anti tuberculosis drugs, adequate nutrition, and treatment for opportunistic infections. This case indicates an emerging need to consider providing facility for HIV drug sensitivity testing at various sites in order to select appropriate second line antiretrovirals that would be of benefit to a patient.
DOI: http://dx.doi.org/10.3126/jnps.v33i2.7699
J Nepal Paediatr Soc. 2013; 33(2):141-143
Downloads
Downloads
Additional Files
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).