Retinopathy of Prematurity: Incidence, Risk Factors & Outcome in North Indian Rural and Semi-urban population

Authors

  • Kamal Parihar Senior Resident, Department of Paediatrics, Netaji Subhash Chandra Bose Subharti Medical College, Swami Vivekanand Subharti University, Subharti Puram, NH-58, Delhi Haridwar Bypass Road, Meerut – 25005, Uttar Pradesh, India.
  • Pradeep Kumar Gupta Assistant Professor, Head of Department, Department of Paediatrics, Netaji Subhash Chandra Bose Subharti Medical College, Swami Vivekanand Subharti University, Subharti Puram, NH-58, Delhi Haridwar Bypass Road, Meerut – 25005, Uttar Pradesh, India
  • Vandana Singh Assistant Professor, Department of Paediatrics,Netaji Subhash Chandra Bose Subharti Medical College, Swami Vivekanand Subharti University, Subharti Puram, NH-58, Delhi Haridwar Bypass Road, Meerut – 25005, Uttar Pradesh, India
  • Sanjay Sharma Assistant Professor, Department of Ophthalmology, Netaji Subhash Chandra Bose Subharti Medical College, Swami Vivekanand Subharti University, Subharti Puram, NH-58, Delhi Haridwar Bypass Road, Meerut – 25005, Uttar Pradesh, India

DOI:

https://doi.org/10.3126/jnps.v42i1.39034

Keywords:

Frequency, Outcome, Predisposing Factors, Retinopathy of Prematurity, Rural North India

Abstract

Introduction: ROP is a challenge due to better premature survival. It has an increasing trend and is a preventable cause of vision loss. Its occurrence, severity and outcome in rural population is poorly studied.

Methods: Ahospital based prospective observational longitudinal study was conducted on babies born at a tertiary care centre. Babies with gestation <32 weeks or birth weight < 1500 g were screened for ROP. Preterm babies of >32 weeks gestation with oxygen requirement, RDS, surfactant use, PDA, neonatal hyperbilirubinemia requiring phototherapy, septicemia, red cell transfusion due to anemia, need for inotropes were also included. Babies with ROP were assessed for severity as also need for intervention and were followed for12 months.

Results: Of the 211 neonates screened, 51 had ROP. Frequency was inversely related to both birth weight and gestational age with no gender difference. Oxygen therapy (p 0.001), RDS (p 0.005), mechanical ventilation (p0.003) and septicemia (p 0.005) were main risk factors. Neonatal hyperbilirubinemia requiring phototherapy was found to be protective (p 0.0005). 15.68% cases required laser photocoagulation. During follow up, ROP regressed in all patients.

Conclusions: Risk factors for ROP included oxygen usage, RDS, mechanical ventilation and septicemia. Blood products or inotropes use was not an independent factor. Neonatal hyperbilirubinemia was protective. When diagnosed early, outcome is good in ROP.

Downloads

Download data is not yet available.
Abstract
73
PDF
127

Downloads

Published

2022-11-27

How to Cite

Parihar, K. ., Kumar Gupta, P. ., Singh, V. ., & Sharma, S. . (2022). Retinopathy of Prematurity: Incidence, Risk Factors & Outcome in North Indian Rural and Semi-urban population. Journal of Nepal Paediatric Society, 42(1), 119–123. https://doi.org/10.3126/jnps.v42i1.39034

Issue

Vol. 42 No. 1 (2022)

Section

Original Articles

License

Copyright (c) 2022 Kamal Parihar, PRADEEP GUPTA, Vandana Singh, Sanjay Sharma

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).