Microbial Resistance Caused by Antibiotic Prophylaxis with Amoxicillin in a Male Infant with Vesicoureteral Reflux

Authors

  • Kazuto Taniguchi Tara Town Hospital, Tara, Japan
  • Sakumo Kii Tara Town Hospital, Tara, Japan
  • Masafumi Oka Department of Paediatrics, Ureshino Medical Centre, Ureshino, Japan
  • Kazuyasu Uemichi Tara Town Hospital, Tara, Japan

DOI:

https://doi.org/10.3126/jnps.v38i3.22662

Keywords:

antibiotic prophylaxis, microbial resistance, vesicoureteral reflux

Abstract

Vesicoureteral reflux is a common condition in infants with urinary tract infection. Although antibiotic prophylaxis to prevent recurrent urinary tract infection is widely performed, its effectiveness remains controversial. Herein we report a seven- month-old boy with vesicoureteral reflux. Antibiotic prophylaxis with amoxicillin caused microbial resistance accompanied by recurrent urinary tract infection. Subsequent antibiotic prophylaxis with sulfamethoxazole-trimethoprim was effective until spontaneous remission of vesicoureteral reflux occurred. Sulfamethoxazole-trimethoprim, but not amoxicillin, should be considered as an agent for antibiotic prophylaxis in infants with vesicoureteral reflux.

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Published

2018-12-31

How to Cite

Taniguchi, K., Kii, S., Oka, M., & Uemichi, K. (2018). Microbial Resistance Caused by Antibiotic Prophylaxis with Amoxicillin in a Male Infant with Vesicoureteral Reflux. Journal of Nepal Paediatric Society, 38(3), 196–199. https://doi.org/10.3126/jnps.v38i3.22662

Issue

Section

Case Reports