Accuracy of Transcutaneous Bilirubinometry in Neonates Receiving Phototherapy

Authors

  • Pallavi Parag Dagli Smt NHL MMC Ahmedabad
  • Snehal Vasava Smt NHL MMC, Ahmedabad

DOI:

https://doi.org/10.3126/jnps.v38i1.17138

Keywords:

Neonatal Jaundice, Indirect Hyperbilirubinemia, JM-103 device, Transcutaneous Bilirubinometry, Total Serum Bilirubin

Abstract

Introduction: Phototherapy remains mainstay of treating neonatal hyperbilirubinemia across gestational age spectrum. Neonates under phototherapy (PTx) require frequent estimation of serum bilirubin (TSB) to monitor disease progression. Transcutaneous bilirubinometer (TcB) is widely used for estimation of TSB with limited data for neonates receiving PTx. The aim of study was to assess the diagnostic accuracy of TcB as compared to TSB in preterm and term infants receiving phototherapy.

Methods: This prospective study analyzed 385 paired TcB-TSB samples from 234 hemodynamically stable preterm (89) and term (145) neonates receiving in-hospital PTx. Indigenous photo-opaque patch was applied to sternum before starting PTx. TcB was measured from patched area of skin using Dräger JM-103 device at 12 and 24 hours during phototherapy within 5 minutes of blood collection for TSB. Linear regression and Bland-Altman plots were used to compare TcB with TSB.

Results: The mean (SD) gestational age and birth weight were 35.8 (2.43) weeks and 2250 (560) grams. Difference of mean of TcB and TSB was ranging between 0.7-1 mg/dl with TcB underestimating TSB. At 12 hours and 24 hours of PTx, the correlation coefficient were (r = 0.84 and 0.81, p<0.01) among preterm and (r = 0.76 and 0.79, p<0.01) among term infants. Bland–Altman plot showed significant agreement between TcB from patched site and TSB in both preterm and term neonates.

Conclusion: TcB demonstrated significant accuracy in predicting TSB in both term and preterm neonates receiving PTx with slight underestimation of TSB. The study showed marginally higher correlation for preterm infants.  

Downloads

Download data is not yet available.
Abstract
748
PDF
638

Author Biographies

Pallavi Parag Dagli, Smt NHL MMC Ahmedabad

Asso. Professor (Pediatrics)

Snehal Vasava, Smt NHL MMC, Ahmedabad

Ex Resident (Pediatrics)

Downloads

Published

2018-11-19

How to Cite

Dagli, P. P., & Vasava, S. (2018). Accuracy of Transcutaneous Bilirubinometry in Neonates Receiving Phototherapy. Journal of Nepal Paediatric Society, 38(1), 1–7. https://doi.org/10.3126/jnps.v38i1.17138

Issue

Vol. 38 No. 1 (2018)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).