Meconium Stained Amniotic Fluid – A Potential Predictor Of Meconium Aspiration Syndrome

Authors

  • P Swain Dept of Paediatrics, Manipal College of Medical Sciences (MCOMS), Pokhara, Nepal
  • A Thapalial Dept of Paediatrics, Manipal College of Medical Sciences (MCOMS), Pokhara, Nepal

DOI:

https://doi.org/10.3126/jnps.v28i1.1397

Keywords:

Meconium Stained Amniotic Fluid, Meconium Aspiration Syndrome and Apgar Score

Abstract

Objective: To identify potential predictors of Meconium Aspiration Syndrome (MAS) in pregnancies complicated by meconium-stained amniotic fluid (MSAF) & to review the incidence, morbidity and mortality of Meconium Aspiration Syndrome (MAS).

Methods: In the period of 2003 to 2006,175 pregnancies with thick meconium-stained AF were delivered; of these, 15 neonates developed MAS and 160 did not. The two groups were compared retrospectively according to maternal findings, pregnancy outcome, and neonatal complications, using univariate analysis (P < 0.05 considered significant) and stepwise multiple logistic regression analysis to identify independent significant factors for prediction of MAS.

Results: Incidence of MSAF was 13.97% and that of MAS was 8.57%. All deliveries associated with thick MSAF had developed MAS. 40% mothers were associated with PROM & prolonged labour. Most common & significant risk factors associated with MAS were increased gestational age, increased cesarean section (LSCS) & low Apgar scores at 1 minute and 5 minute. Mortality rate was 6.66% & mechanical ventilation was used in only 1(6.66%) case.

Conclusion: MAS are associated with higher incidence of LSCS, lower 1 minute & 5 minute Apgar score & higher gestational weeks. 40% mothers were associated with PROM & prolonged labour. The neonatal morbidity & mortality is significantly more frequent in relation to thick meconium stained amniotic fluid. Specific delivery room resuscitation procedure, early diagnosis & proper management can prevent development of MAS as well as morbidity & mortality.

Key words: Meconium Stained Amniotic Fluid, Meconium Aspiration Syndrome and Apgar Score.  

DOI = 10.3126/jnps.v28i1.1397

J. Nepal Paediatr. Soc. Vol.28(1) p.3-6

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How to Cite

Swain, P., & Thapalial, A. (2008). Meconium Stained Amniotic Fluid – A Potential Predictor Of Meconium Aspiration Syndrome. Journal of Nepal Paediatric Society, 28(1), 3–6. https://doi.org/10.3126/jnps.v28i1.1397

Issue

Vol. 28 No. 1 (2008)

Section

Original Articles

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