Multi Organ Dysfunction in Term Neonates with Perinatal Asphyxia

Authors

  • Aditya Vemuri Bharati Vidyapeeth Deemed University Medical College, Pune - 411046
  • Sanjay Lalwani Department of Paediatrics, Bharati Vidyapeeth Deemed University Medical College, Pune - 411046

DOI:

https://doi.org/10.3126/jnps.v35i3.12156

Keywords:

Perinatal asphyxia, Multi-organ dysfunction, Term neonates

Abstract

Introduction: Multiorgan dysfunction (MOD) is one of the four consensus based criteria for the diagnosis of intrapartum asphyxia. The theoretical concept behind MOD is the diving reflex -conservation of blood flow to vital organs at the cost of non-vital organs. The objective of this study was to assess the patterns of involvement of each major organ/system in term asphyxiated neonates.

Material and Methods: This was a hospital based prospective study. Sixty term neonates who had suffered perinatal asphyxia were assessed for central nervous system, kidney, cardiovascular system, gastrointestinal system and liver dysfunction.

 Results: Out of 60 eligible neonates, 57 (95%) had evidence of at least one organ dysfunction. Cardiovascular system involvement (95%) was most common, followed by renal system (37%), hepatic system (22%), central nervous system and hematological system (20% each) and finally, gastrointestinal tract (8%).

Conclusion: MOD is frequently associated with perinatal asphyxia with cardiovascular system being the most commonly affected.

J Nepal Paediatr Soc 2015;35(3):307-311.

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Published

2016-06-02

How to Cite

Vemuri, A., & Lalwani, S. (2016). Multi Organ Dysfunction in Term Neonates with Perinatal Asphyxia. Journal of Nepal Paediatric Society, 35(3), 307–311. https://doi.org/10.3126/jnps.v35i3.12156

Issue

Vol. 35 No. 3 (2015)

Section

Brief Reports/Case Reports/Case Series

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