Hereditary Spherocytosis: A Case Report

Authors

Keywords:

anemia, hereditary spherocytosis, osmotic fragility test, red blood cell

Abstract

Introduction: Hereditary spherocytosis is a red cell membrane disorder that causes hemolytic anemia. Due to defective cell membrane, red cells are spherical shaped and result in their early lysis. Osmotic fragility of spherocytic red cell is increased.

Case report: A 22 year old female presented with chief complain of abdominal pain. Initially she was diagnosed as cholelithiasis. Under laboratory evaluation she was found to be anemic with reticulocytosis. In peripheral blood smear, spherocytes were moderately distributed. Antihuman globulin test was negative but osmotic fragility was high. Hence, she was confirmed as case of hereditary spherocytosis.

Conclusion: Hereditary spherocytosis is a rare red cell disorder and its diagnosis can be made by osmotic fragility test.

 

DOI: https://doi.org/10.22502/jlmc.v6i1.202

Downloads

Download data is not yet available.
Abstract
1326
PDF
1170

Author Biography

Surendra Koju, Dhulikhel Hospital - Kathmandu University Hospital

Medical Hematologist,

Department of Pathology

Downloads

Published

2018-06-27

How to Cite

Koju, S., & Makaju, R. (2018). Hereditary Spherocytosis: A Case Report. Journal of Lumbini Medical College, 6(1), 41–43. Retrieved from https://nepjol.info/index.php/JLMC/article/view/20462

Issue

Vol. 6 No. 1 (2018)

Section

Case Reports

License

The Journal of Lumbini Medical College (JLMC) publishes open access articles under the terms of the Creative Commons Attribution(CC BY) License which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

JLMC requires an exclusive licence allowing to publish the article in print and online.

The corresponding author should read and agree to the following statement before submission of the manuscript for publication,

License agreement
In submitting an article to Journal of Lumbini Medical College (JLMC) I certify that:

  1. I am authorized by my co-authors to enter into these arrangements.
  2. I warrant, on behalf of myself and my co-authors, that:
    • the article is original, has not been formally published in any other peer-reviewed journal, is not under consideration by any other journal and does not infringe any existing copyright or any other third party rights;
    • I am/we are the sole author(s) of the article and have full authority to enter into this agreement and in granting rights to JLMC are not in breach of any other obligation;
    • the article contains nothing that is unlawful, libellous, or which would, if published, constitute a breach of contract or of confidence or of commitment given to secrecy;
    • I/we have taken due care to ensure the integrity of the article. To my/our - and currently accepted scientific - knowledge all statements contained in it purporting to be facts are true and any formula or instruction contained in the article will not, if followed accurately, cause any injury, illness or damage to the user.
  3. I, and all co-authors, agree that the article, if editorially accepted for publication, shall be licensed under the Creative Commons Attribution License 4.0. If the law requires that the article be published in the public domain, I/we will notify JLMC at the time of submission, and in such cases the article shall be released under the Creative Commons 1.0 Public Domain Dedication waiver. For the avoidance of doubt it is stated that sections 1 and 2 of this license agreement shall apply and prevail regardless of whether the article is published under Creative Commons Attribution License 4.0 or the Creative Commons 1.0 Public Domain Dedication waiver.
  4. I, and all co-authors, agree that, if the article is editorially accepted for publication in JLMC, data included in the article shall be made available under the Creative Commons 1.0 Public Domain Dedication waiver, unless otherwise stated. For the avoidance of doubt it is stated that sections 1, 2, and 3 of this license agreement shall apply and prevail.

Please visit Creative Commons web page for details of the terms.