The Efficacy of Ketamine Gargle in Attenuating Postoperative Sore Throat: A Randomized Control Trial

Authors

  • Ram Prashad Sharma Department of Anesthesiology Lumbini Medical College Teaching Hospital, Palpa
  • Pradip Raj Vaidya Department of Anesthesiology, National Academy of Medical Sciences, Kathmandu
  • Man Bahadur Chand Department of Anesthesiology, National Academy of Medical Sciences, Kathmandu

Keywords:

endotracheal, intubation, ketamine, pharyngitis, postoperative

Abstract

Introduction: Postoperative sore throat (POST) is a common complication of general anesthesia with endotracheal intubation that affects the patient satisfaction after surgery. The aim of the study was to compare the effectiveness of ketamine gargle with placebo in preventing POST after endotracheal intubation.

Methods: Sixty eight patients scheduled for elective surgery under general anesthesia were enrolled in this study. Patients were randomly allocated into two groups, 33 in study group and 35 in control group. Study group patients were asked to gargle with ketamine (50 mg in 1 ml mixed with 29 ml of drinking water) 10 minutes before induction for 30 seconds. Controls were made to do so with 30 ml of drinking water. POST was graded at one, two, four, and 24 hrs after operation on a four-point scale (0-3). The outcome measures were compared between two groups in terms of occurrence of POST and severity of POST at one, two, four, and 24 hr to determine the efficacy of ketamine.

Results: Occurrence of POST was significantly less in study group at four hours. Severity of POST was significantly low in study group at one, two and four hours as compared to that in controls. It was comparable at 24 hours.

Conclusion: Ketamine gargle significantly reduced the occurrence and severity of POST.

DOI: https://doi.org/10.22502/jlmc.v3i1.61

Downloads

Download data is not yet available.
Abstract
607
PDF
620

Downloads

Published

2016-11-28

How to Cite

Sharma, R. P., Vaidya, P. R., & Chand, M. B. (2016). The Efficacy of Ketamine Gargle in Attenuating Postoperative Sore Throat: A Randomized Control Trial. Journal of Lumbini Medical College, 3(1), 8–11. Retrieved from https://nepjol.info/index.php/JLMC/article/view/16087

Issue

Vol. 3 No. 1 (2015)

Section

Original Research Articles

License

The Journal of Lumbini Medical College (JLMC) publishes open access articles under the terms of the Creative Commons Attribution(CC BY) License which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

JLMC requires an exclusive licence allowing to publish the article in print and online.

The corresponding author should read and agree to the following statement before submission of the manuscript for publication,

License agreement
In submitting an article to Journal of Lumbini Medical College (JLMC) I certify that:

  1. I am authorized by my co-authors to enter into these arrangements.
  2. I warrant, on behalf of myself and my co-authors, that:
    • the article is original, has not been formally published in any other peer-reviewed journal, is not under consideration by any other journal and does not infringe any existing copyright or any other third party rights;
    • I am/we are the sole author(s) of the article and have full authority to enter into this agreement and in granting rights to JLMC are not in breach of any other obligation;
    • the article contains nothing that is unlawful, libellous, or which would, if published, constitute a breach of contract or of confidence or of commitment given to secrecy;
    • I/we have taken due care to ensure the integrity of the article. To my/our - and currently accepted scientific - knowledge all statements contained in it purporting to be facts are true and any formula or instruction contained in the article will not, if followed accurately, cause any injury, illness or damage to the user.
  3. I, and all co-authors, agree that the article, if editorially accepted for publication, shall be licensed under the Creative Commons Attribution License 4.0. If the law requires that the article be published in the public domain, I/we will notify JLMC at the time of submission, and in such cases the article shall be released under the Creative Commons 1.0 Public Domain Dedication waiver. For the avoidance of doubt it is stated that sections 1 and 2 of this license agreement shall apply and prevail regardless of whether the article is published under Creative Commons Attribution License 4.0 or the Creative Commons 1.0 Public Domain Dedication waiver.
  4. I, and all co-authors, agree that, if the article is editorially accepted for publication in JLMC, data included in the article shall be made available under the Creative Commons 1.0 Public Domain Dedication waiver, unless otherwise stated. For the avoidance of doubt it is stated that sections 1, 2, and 3 of this license agreement shall apply and prevail.

Please visit Creative Commons web page for details of the terms.