Clinico pathological study of Odontogenic cysts and tumors in a Tertiary care Dental hospital of Nepal
DOI:
https://doi.org/10.3126/jkmc.v11i1.45495Keywords:
Odontogenic cysts, Odontogenic tumour, PathologyAbstract
Background: Diagnosis of odontogenic cysts and tumours requires detailed clinical, radiographical, and histopathological findings. Fourth edition WHO 2017, classification of Head and Neck lesions, reclassified odontogenic cysts and tumours.
Objectives: To know relative frequency of odontogenic cysts and tumours according to WHO 2017 classification and to know their clinico-pathological characteristics in selected population of Nepal.
Methods: An analytical cross-sectional study was done in 163 biopsies. Data were obtained conveniently from records of patients diagnosed with odontogenic cysts and tumours from April 2014-2021. Cases with complete clinical details were included whereas non-odontogenic cysts, oral soft tissue, and salivary gland lesions were excluded. Reclassification according to WHO 2017 classification was done. Age, gender, site, clinical presentations, and histological type were analysed using SPSS v.21.
Results: In total of 163 biopsies, 120 (73.62%) cases were of odontogenic cysts and 43 (26.38%) cases were of odontogenic tumours. The mean age of occurrence for cysts was 33.35 ± 16.67 years and for tumours was 28.91 ± 13.96 years. Radicular cyst (49/120, 40.83%) and conventional ameloblastoma (23/43 53.48%) were the commonest cysts and tumours. Male (67/120, 55.83%) and female (24/43, 55.81%) predisposition was seen in cysts and tumours. Mandibular middle and posterior region were commonly affected in both cysts (58/162, 35.8%) and tumours (38/53, 71.7%).
Conclusion: Increased frequency of radicular cysts and conventional ameloblastoma were appreciated with male predisposition in tumours and female predisposition in cysts. Both cysts and tumours were common in second to third decade of life affecting middle and posterior region of mandible.
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References
Ramachandra S, Shekar PC, Prasad S, Kumar KK, Reddy GS, Prakash KL, et al. Prevalence of odontogenic cysts and tumours: A retrospective clinico-pathological study of 204 cases. SRM J Res Dent Sci. 2014 Jul 1;5(3):170. [Full Text]
Izgi E, Mollaoglu N, Simsek MB. Prevalence of odontogenic cysts and tumours on turkish sample according to latest classification of world health organisation: A 10-year retrospective study. Niger J Clin Pract. 2021 Mar 1;24(3):355. [Full Text]
Wright JM, Vered M. Update from the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumours. Head Neck Pathol. 2017 Mar 1;11(1):68-77. [PubMed | Full Text]
Al-Rawi NH, Awad M, Al-Zuebi IE, Hariri RA, Salah EW. Prevalence of odontogenic cysts and tumours among UAE population. J Orofac Sci. 2013 Jul 1;5(2):95. [Full Text]
Borges LB, Fechine FV, Mota MR, Sousa FB, Alves AP. Odontogenic lesions of the jaw: A clinical? pathological study of 461 cases. Rev Gau?ch Odontol 2012; 60(1):71?8. [Full Text]
Soluk-Tekke?in M, Wright JM. The world health organization classification of odontogenic lesions: A summary of the changes of the 2017 (4th) Edition. Turk Patoloji Derg. 2018;34(1):1-18. [PubMed | Full Text]
Silva K, Alves A, Correa M, Etges A, Vasconcelos AC, Gomes AP, et al. Retrospective analysis of jaw biopsies in young adults. A study of 1599 cases in Southern Brazil. Med Oral Patol Oral Cir Bucal. 2017;22(6):e702-e707. [PubMed | Full Text]
Kambalimath DH, Kambalimath HV, Agrawal SM, Singh M, Jain N, Anurag B, et al. Prevalence and distribution of odontogenic cyst in Indian population: A 10-year retrospective study. J Maxillofac Oral Surg. 2014;13(1):10-5. [PubMed | Full Text | DOI ]
Sivapathasundharam B. Shafer’s Textbook of Oral Pathology. 8th ed. Elsevier Health Sciences; 2016. [Full Text]
Avelar RL, Antunes AA, de Santana Santos T, de Souza Andrade ES, Dourado E. Odontogenic tumours: Clinical and pathology study of 238 cases. Rev Bras Otorhinolaryngol. 2008;74(5):668-73. [Full Text]
Nalabolu GR, Mohiddin A, Hiremath SK, Manyam R, Bharath TS, Raju PR. Epidemiological study of odontogenic tumours: An institutional experience. J Infect Public health. 2017 May 1;10(3):324-30. [Full Text]
Jaeger F, de Noronha MS, Silva MLV, Amaral MBF, Grossmann SMC, Horta MCR, et al. Prevalence profile of odontogenic cysts and tumours on Brazilian sample after the reclassification of odontogenic keratocyst. J Craniomaxillofac Surg. 2017;45:267?70. [PubMed | DOI]Krishnapillai R, Angadi PV. A clinical, radiographic, and histologic review of 73 cases of ameloblastoma in an Indian population. Quintessence Int. 2010 May;41(5):e90-100. [PubMed | Full Text]
da Silva LP, Serpa MS, Tenório JR, do Nascimento GJ, de Souza-Andrade ES, Veras-Sobral AP. Retrospective study of 289 odontogenic tumours in a Brazilian population. Med Oral Pathol Oral Cir Bucal. 2016 May 1;21(3):e271-5. [Pub Med | Full Text]
Jaafari-Ashkavandi Z, Akbari B. Clinicopathologic study of ?ntra-osseous lesions of the jaws in Southern Iranian population. J Dent (Shiraz).2017;18:259-64. [PubMed | Full Text]
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