Computed tomography findings of focal lung lesion and their pathological correlations

Authors

  • Saroj Sharma National Academy of Medical Sciences, Kathmandu
  • Hom Prasad Pant National Academy of Medical Sciences, Kathmandu
  • Swoyam Prakash Pandit National Academy of Medical Sciences, Kathmandu

DOI:

https://doi.org/10.3126/jkmc.v4i2.15036

Keywords:

Computerized Tomography scan, Lung mass, Malignancy

Abstract

Background: Focal lung masses are common radiological fi ndings which need to be characterized to plan management. Suspicious lesions require invasive investigations and aggressive treatment. However, likely benign lesions require no invasive investigations.

Objectives: We aimed to correlate the computerized tomography fi ndings of focal lung lesions with pathological diagnoses.

Methods: A total of 56 patients were enrolled in the study. Plain and contrast enhanced computerized tomography scan of chest was done in spiral computerized tomography. Radiologist’s computerized tomography reports were obtained. Pathological diagnosis were followed in all cases and recorded. Computerized tomography reports were compared with pathological reports and validity of computerized tomography in predicting the nature of lung lesion was assessed.

Results: Overall, squalors cell carcinoma was the most common histological cell type (46.34%) followed by adenocarcinoma (41.46%). In 95.12% of total cases, size of the malignant lesion was more than 3cm. Squalors cell Carcinoma was the most common tumor located centrally (71.42%) and adenocarcinoma peripherally (55.55%). Spiculated margin was most commonly associated in malignant lesions. Among morphological characters, chest wall invasion and meditational invasion were statistically significant for malignancy. Contrast enhancement more than 20 hounsfield unit had more than 80% sensitivity and specificity for malignant lesions. Sensitivity of computerized tomography combining all morphological characteristics for depicting malignancy was 97.6% and specificity was 46.7%.

Conclusion: The present study showed that contrast enhanced computerized tomography provides more precise tumor localization, characterization and intrathoracic extension to differentiate benign from malignant lung lesion. Enhancement of the lesion is more specific for malignancy than other morphological characteristic.

Journal of Kathmandu Medical College, Vol. 4, No. 2, Issue 12, Apr.-Jun., 2015, page: 59-64

Downloads

Download data is not yet available.
Abstract
1476
PDF
543

Author Biographies

Saroj Sharma, National Academy of Medical Sciences, Kathmandu

Consultant Radiologist

Hom Prasad Pant, National Academy of Medical Sciences, Kathmandu

MD Resident

Swoyam Prakash Pandit, National Academy of Medical Sciences, Kathmandu

Associate Professor

Downloads

Published

2016-05-31

How to Cite

Sharma, S., Pant, H. P., & Pandit, S. P. (2016). Computed tomography findings of focal lung lesion and their pathological correlations. Journal of Kathmandu Medical College, 4(2), 59–64. https://doi.org/10.3126/jkmc.v4i2.15036

Issue

Vol. 4 No. 2 (2015)

Section

Original Research Articles

License

Copyright © Journal of Kathmandu Medical College
The ideas and opinions expressed by authors or articles summarized, quoted, or published in full text in this journal represent only the opinions of the authors and do not necessarily reflect the official policy of Journal of Kathmandu Medical College or the institute with which the author(s) is/are affiliated, unless so specified.

Authors convey all copyright ownership, including any and all rights incidental thereto, exclusively to JKMC, in the event that such work is published by JKMC. JKMC shall own the work, including 1) copyright; 2) the right to grant permission to republish the article in whole or in part, with or without fee; 3) the right to produce preprints or reprints and translate into languages other than English for sale or free distribution; and 4) the right to republish the work in a collection of articles in any other mechanical or electronic format.