Lipid profile in different grades of Ultrasonic Non-Alcoholic Fatty Liver Disease

Authors

  • Khem Raj Bhusal Green City Hospital, Kathmandu http://orcid.org/0000-0003-0813-2019
  • Rabindra Simkhada Shahid Gangalal National Heart Centre
  • Pramod Nepal Manmohan Memorial Teaching Hospital

DOI:

https://doi.org/10.3126/jcmsn.v13i2.17773

Keywords:

Dyslipidemia, Fatty liver disease, Lipid profile

Abstract

Background & Objectives: This study was conducted with objective of studying the lipid abnormalities in patients with non-alcoholic fatty liver disease diagnosed on the basis of ultrasound.

Materials & Methods: Total 100 patients consisting of 67 males and 37 females diagnosed as Non-alcoholic fatty liver disease on the basis of ultrasound were included in the study. Laboratory values of different lipid parameters were compared in different grades of these patients.

Results: Out of total 100 cases, mild nonalcoholic fatty liver disease was found in 83 %, moderate in 17 % and severe in none of the participants. Age of the participants ranged from 26 to 79 years with mean being 45 ± 11.99 years. Presence of dyslipidemia was found in 94 % of the cases. Triglycerides, total cholesterol and low density lipoprotein levels were raised in 59, 53, 72% of the cases respectively and High density lipoprotein level was decreased in 57% of participants. There was significant positive correlation of presence of non-alcoholic fatty liver disease with increasing levels of serum total cholesterol (P value <0.001), low density lipoprotein (P value <0.001) and triglyceride (P value <0.001) and significantly decreasing high density lipoprotein (P value <0.001). Whereas increasing grades of non-alcoholic fatty liver disease weren’t significantly associated with increasing level of lipid abnormalities.

Conclusion: This study showed the high prevalence of dyslipidemia in non-alcoholic fatty liver patients. Early detection with simple non-invasive ultrasonography is very useful to detect dyslipidemic patients.

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Published

2017-07-17

How to Cite

Bhusal, K. R., Simkhada, R., & Nepal, P. (2017). Lipid profile in different grades of Ultrasonic Non-Alcoholic Fatty Liver Disease. Journal of College of Medical Sciences-Nepal, 13(2), 258–261. https://doi.org/10.3126/jcmsn.v13i2.17773

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Section

Original Articles