Erythromycin Induced Carbamazepine Toxicity- A Preventable Drug Interaction

Authors

  • Devendra Shrestha Department of Pediatrics, KIST Medical College, Imadol, Lalitpur,
  • AK Dhakal Department of Pediatrics, KIST Medical College, Imadol, Lalitpur,
  • KK Singh Department of Pediatrics, KIST Medical College, Imadol, Lalitpur,

Keywords:

Carbamazepine toxicity, Drug toxicity, Erythromycin-Carbamazepine interaction

Abstract

A drug interaction between Erythromycin and Carbamazepine is well established and harmful effects of Carbamazepine toxicity can be avoided. We report a patient who developed features of Carbamazepine toxicity namely ataxia, vomiting and nystagmus within 24 hours of oral Erythromycin with high serum Carbamazepine level and improved after discontinuation of Erythromycin with returning of serum Carbamazepine level to therapeutic range. Awareness among health professionals, patient education, proper record keeping and strengthening pharmacy services are essential to prevent such drug interactions.

Journal of Chitwan Medical College 2013; 3(4); 52-53

DOI: http://dx.doi.org/10.3126/jcmc.v3i4.9556

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Published

2014-01-11

How to Cite

Shrestha, D., Dhakal, A., & Singh, K. (2014). Erythromycin Induced Carbamazepine Toxicity- A Preventable Drug Interaction. Journal of Chitwan Medical College, 3(4), 52–53. Retrieved from https://nepjol.info/index.php/JCMC/article/view/9556

Issue

Vol. 3 No. 4 (2013)

Section

Case Reports