CNS Histiocytosis- Rare Disease with An Unusual Manifestation

Authors

  • Saurabh Sadekar Department of Neurology, Manipal Hospital, Bangalore 560017 India
  • Alluri Swathi Department of Neurology, Yashoda Hospital, Somajiguda, Hyderabad 500082 India
  • Kandadai Rukmini Mridula Department of Neurology, City Neuro Center, Hyderabad, India
  • N. Chakradhar Department of Neurology, Yashoda Hospital, Somajiguda, Hyderabad 500082 India
  • C. Arpita Department of Radiology, Yashoda Hospital, Somajiguda, Hyderabad 500082 India
  • Anand Balasubramanian Department of Neurosurgery, Yashoda Hospital, Secunderabad 500003 India
  • VCS Srinivasarao Bandaru Department of Neurology, Yashoda Hospital, Somajiguda, Hyderabad 500082 India
  • Jaydip Ray Chaudhuri Department of Neurology, Yashoda Hospital, Somajiguda, Hyderabad 500082 India

DOI:

https://doi.org/10.3126/jaim.v12i2.62077

Keywords:

Histiocytosis, Pituatory gland, Diabetes Insipidus, Brainstem involvement, MIB-1 stain, steroid responsive, immunohistochemistry

Abstract

CNS histiocytosis is a rare and debilitating disease with multiple presentations. We here present a rare case of histiocytosis in a 4 year old child manifesting with diplopia as the sole neurological symptom. The patient had only saccadic abnormalities on examination and lesions in tectal pons and cerebellum. Initially considering the possibility of demyelinating disorder, steroids were given with partial resolution of signs but no improvement in signs or MRI imaging. Biopsy gave the diagnosis. The diagnosis of CNS histiocytosis should be considered even in patients with few symptoms and actively evaluated for.

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Published

2023-12-31

How to Cite

Sadekar, S., Swathi, A., Mridula, K. R., Chakradhar, N., Arpita, C., Balasubramanian, A., Bandaru, V. S., & Chaudhuri, J. R. (2023). CNS Histiocytosis- Rare Disease with An Unusual Manifestation. Journal of Advances in Internal Medicine, 12(2), 42–44. https://doi.org/10.3126/jaim.v12i2.62077

Issue

Section

Case Reports