Analgesic effects of intra-articular ropivacaine following arthroscopic knee surgery: Results of a double-blind, randomized controlled trial between two different doses

Authors

  • Rajdip Hazra Department of Anesthesiology, Nilratan Sircar Medical College and Hospital, Kolkata
  • Md. Babrak Manuar Department of Anesthesiology, Nilratan Sircar Medical College and Hospital, Kolkata
  • SM Manjunatha Department of Anesthesiology, Nilratan Sircar Medical College and Hospital, Kolkata
  • Sisir Chakraborty Department of Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata
  • Kaushik Ghosh Department of Medicine, Malda Medical College and Hospital, Malda, West Bengal, India
  • Rajarshi Basu Department of Pediatric Medicine, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal
  • Md. Nurejjaman Department of Anesthesiology, Apollo Gleneagles Hospital, Kolkata, India
  • Arun N Kumar Department of Medicine, Mysore Medical College, Mysore, Karnataka
  • SK Yathish Department of Anesthesiology, Hindu Rao Hospital and NDMC Medical College, New Delhi, India

DOI:

https://doi.org/10.3126/ajms.v6i1.9703

Keywords:

Ropivacaine, fentanyl, dexmedetomidine, analgesia, intra-articular route, arthroscopic knee surgery

Abstract

Background: Though local anesthetic agents are widely used to provide postoperative analgesia in intra-articular route, their efficacy is not accepted universally.

Objective: The present study has been conducted to compare the analgesic effects of intra-articular ropivacaine between two different doses following arthroscopic knee surgery.

Study design: Double-blinded randomized controlled trial. Total 60 patients of ASA (American Society of Anesthesiologists) physical status I and II, 34 male and 26 female, aged between 18 to 60 years, were randomized into 3 groups receiving 10 ml normal saline, 10 ml 0.5% ropivacaine and 10 ml 0.75% ropivacaine respectively, administered in intra-articular space at the end of operation.

Results: Ropivacaine groups had significantly delayed first post-operative rescue analgesic request with significantly lesser requirement of rescue analgesia in first 24 hours (p<0.001 in both cases). Except 6th post-operative hours, ropivacaine groups also showed significantly less VAS scores (Visual Analogue Scale) up to 12 hours post-operatively (p<0.05).

Conclusion: In our double-blinded randomized controlled trial, administration of intra-articular 0.75% ropivacaine showed superior analgesic efficacy following arthroscopic knee surgery. Further, larger trials are needed to confirm our findings.

DOI: http://dx.doi.org/10.3126/ajms.v6i1.9703

Asian Journal of Medical Sciences Vol.6(1) 2015 81-86

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Published

2014-07-25

How to Cite

Hazra, R., Manuar, M. B., Manjunatha, S., Chakraborty, S., Ghosh, K., Basu, R., Nurejjaman, M., Kumar, A. N., & Yathish, S. (2014). Analgesic effects of intra-articular ropivacaine following arthroscopic knee surgery: Results of a double-blind, randomized controlled trial between two different doses. Asian Journal of Medical Sciences, 6(1), 81–86. https://doi.org/10.3126/ajms.v6i1.9703

Issue

Vol. 6 No. 1 (2015)

Section

Original Articles

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