Image Guided Radiotherapy by CBCT based Position Verification in High Risk Carcinoma Prostate - an Indian experience and review of literature
DOI:
https://doi.org/10.3126/ajms.v5i2.8382Keywords:
Image guided radiotherapy, CBCT scan, Carcinoma prostate, Dose escalation.Abstract
Introduction-External beam radiotherapy is one of the principle treatment options for locally advanced prostate cancer. Over the past several decades, RT techniques have evolved to allow higher doses of radiation to be administered safely. We report our experience of Image guided intensity modulated radiotherapy (IGRT) and CBCT based position verification.
Material and methods- In this study we are presenting data of 17 consecutive patients that were treated from august 2009 to october 2010. All patients received 76 -78 Gy Gy to clinical target volume for primary disease. Daily online matching was performed by using KV CBCT scan before treatment. In each patient, soft tissue (prostate) matching was done by the radiation oncologist.
Results – Median Follow up of our patients is 16 months with minimum follow up of 13 months. 3(17.6%) patients developed grade 2 acute rectal toxicity and 4 (23.5%) bladder toxicity. Till date none of our patients had late bladder or rectal toxicity. None of our patient developed local recurrence.
Conclusion-Our study concludes that we can follow the dose escalation with CBCT based position verification .With CBCT we can consider entire prostate and normal structures volume for localization.
DOI: http://dx.doi.org/10.3126/ajms.v5i2.8382
Asian Journal of Medical Science, Volume-5(2014): 14-20
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