Bacteriological profile of blood stream infections among febrile patients attending a tertiary care centre of Western Nepal

Authors

  • Dharm Raj Bhatta Manipal College of Medical sciences, Pokhara
  • Abhishek Gaur Manipal College of Medical sciences, Pokhara
  • HS Supram Manipal College of Medical sciences, Pokhara

DOI:

https://doi.org/10.3126/ajms.v4i3.8165

Keywords:

Blood stream infections, enteric fever, Escherichia coli, Pseudomonas aeruginosa, Salmonella paratyphi A.

Abstract

Background Blood stream infections (BSI) are significant cause of morbidity and mortality in the world. This study was conducted to determine the common bacterial agents associated with BSI with their antimicrobial susceptibility patterns in a tertiary care centre in the Western region of Nepal.

Method This cross-sectional study was conducted for a period of two years from May 2010 to May 2012. All patients with fever (temperature ≥ 38°C) were included in the study.

Results A total of 4,145 patients with febrile illness were included in this study, bacterial agents were isolated in 251 (6%) cases. Common bacterial isolates were Salmonella spp., Klebsiella pneumoniae, Escherichia coli, Pseudomonas species, Acinetobacter species, Staphylococcus aureus and Coagulase negative Staphylococci. Paratyphoid fever (Caused by S. Paratyphi A) is more common than typhoid fever. The members of Enterobacteriaceae were found to be resistant to ampicillin and cefazolin. Majority of the nonfermenters were found to be sensitive to most antibiotics. Gentamicin and Ciprofloxacin were sensitive to majority of gram positive bacteria.

Conclusion Gram-negative bacteria were the predominant causes of BSIs. The occurrence of drug resistance among the isolated bacteria is of great concern. Imipenem showed 100% sensitivity against Pseudomonas aeruginosa indicating lack or low level of MBL activity.

DOI: http://dx.doi.org/10.3126/ajms.v4i3.8165

Asian Journal of Medical Sciences 4(2013) 92-98

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Author Biographies

Dharm Raj Bhatta, Manipal College of Medical sciences, Pokhara

Lecturer, Department of Microbiology

Abhishek Gaur, Manipal College of Medical sciences, Pokhara

Assistant Professor, Department of Microbiology

HS Supram, Manipal College of Medical sciences, Pokhara

Lecturer, Department of Microbiology

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Published

2013-06-20

How to Cite

Bhatta, D. R., Gaur, A., & Supram, H. (2013). Bacteriological profile of blood stream infections among febrile patients attending a tertiary care centre of Western Nepal. Asian Journal of Medical Sciences, 4(3), 92–98. https://doi.org/10.3126/ajms.v4i3.8165

Issue

Vol. 4 No. 3 (2013)

Section

Original Articles

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