Phytochemical and Antimicrobial Properties of the Aqueous Root Extract of Triclisia dictyophylla

Authors

  • Anslem O Ajugwo Department of Haematology and Blood Transfusion, Madonna University Elele
  • Anthony C Ezimah Department of Physiology/Anatomy, Federal University Ndufu Abakaliki Ebonyi State
  • Francis M Awah Department of Biochemistry, Madonna University Elele
  • Philippe E Mounbegna Department of Pharmacology, Anambra State University Uli
  • Celestine C Azikiwe Department of Pharmacology, Anambra State University Uli

DOI:

https://doi.org/10.3126/ajms.v4i1.7846

Keywords:

Triclisia dictyophylla, phytochemical, antimicrobial, antifungal, antibiotics

Abstract

Triclisia dictyophylla have been used traditionally for the treatment of different ailments. The root was therefore subjected to phytochemical analysis and antimicrobial/antifungal activity against some hospital-strain disease causing microorganisms. Standard methods were used for the phytochemical screening. The extract was subjected to antimicrobial/antifungal activity using

Staphylococcus aureus, Escherichia coli, Klebsiella spp, Pseudomonas aeruginosa and Candida albicans. The sensitivity pattern was compared to that of ciprofloxacin, cotrimoxazole and ofloxacin. Phytochemical analysis revealed mostly alkaloids and protein while tannins, glycoside and saponin were revealed in trace (+) amounts. The extract showed a good antimicrobial activity on Staphylococcus aureus isolated from sputum and on E. coli from both urine and sputum with no antifungal activity. The extract contains active components which could be harnessed for formulation of antibiotics.

DOI: http://dx.doi.org/10.3126/ajms.v4i1.7846  

Asian Journal of Medical Sciences 4(2013) 15-20

 

Downloads

Download data is not yet available.
Abstract
662
PDF
719

Downloads

Published

2013-04-24

How to Cite

Ajugwo, A. O., Ezimah, A. C., Awah, F. M., Mounbegna, P. E., & Azikiwe, C. C. (2013). Phytochemical and Antimicrobial Properties of the Aqueous Root Extract of Triclisia dictyophylla. Asian Journal of Medical Sciences, 4(1), 15–20. https://doi.org/10.3126/ajms.v4i1.7846

Issue

Vol. 4 No. 1 (2013)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).