Need of Improvement in Timing of Prophylactic Antibiotic in Elective Surgery

Authors

  • J N Shah Department of surgery, Patan Hospital, Patan Academy of Health Science (PAHS), Lalitpur, Kathmandu
  • S B Maharjan Department of surgery, Patan Hospital, Patan Academy of Health Science (PAHS), Lalitpur, Kathmandu
  • K Manandhar Department of surgery, Patan Hospital, Patan Academy of Health Science (PAHS), Lalitpur, Kathmandu

DOI:

https://doi.org/10.3126/ajms.v2i3.5610

Keywords:

antibiotic prophylaxis, guidelines, protocol, surgical site infection

Abstract

Objective: Infections in surgery are major concern of morbidity, mortality, and costs. Timely antibiotic prophylaxis (AP) before incision ensures optimum concentration of AP in blood and tissues to prevent surgical site infections (SSIs). However, proper timing of AP remains problematic as reported by various studies, though none so far from  local institutions in Nepal. Aim of this cross sectional observation study was to assess and address the issues of timing of AP and need for improvements.

Material & Methods: Convenient sample target of 100 cases of preoperative AP were studied from Oct 1 to Oct 30, 2010. Data were prospectively entered in predesigned ‘AP form’ for all major elective surgeries, except obstetric cases, who received AP of intravenous Cefazoline 1 g as per existing hospital protocol. Time of AP administration in respect to incision time was analyzed.

Results: There were 125 cases during study period. Majority, 81% received AP before incision, while 19% had AP after the incision. Only 1% of patients received AP within recommended period within 60 to 30 minutes before incision.

Conclusion: Current practice of antibiotic prophylaxis (AP) at our institutions needs improvement as per standard guidelines of AP within 60 to 30 minutes before incision.

DOI: http://dx.doi.org/10.3126/ajms.v2i3.5610

Asian Journal of Medical Sciences 2 (2011) 207-211

 

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Published

2012-04-24

How to Cite

Shah, J. N., Maharjan, S. B., & Manandhar, K. (2012). Need of Improvement in Timing of Prophylactic Antibiotic in Elective Surgery. Asian Journal of Medical Sciences, 2(3), 207–211. https://doi.org/10.3126/ajms.v2i3.5610

Issue

Vol. 2 No. 3 (2011)

Section

Original Articles

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