Association of thyroid function and obesity with chronic obstructive pulmonary disease: An observational cross-sectional study

Authors

  • Deepak Singh District TB Officer, Amethi, Uttar Pradesh, India
  • Anjuman Chaudhary Associate Professor, Department of Community Medicine, RDASMC, Ayodhya, Uttar Pradesh, India https://orcid.org/0000-0001-6350-6955
  • Atul Kumar Singh Senior Resident, Department of Pulmonary Medicine, Autonomous State Medical College, Etah, Uttar Pradesh, India
  • Abhishek Singh Assistant Professor, Department of Pulmonary Medicine, MLN Medical College, Prayagraj, Uttar Pradesh, India

DOI:

https://doi.org/10.3126/ajms.v14i11.55662

Keywords:

Obesity; Thyroid dysfunction; Chronic obstructive pulmonary disease; Hypothyroid

Abstract

Background: Chronic obstructive pulmonary disease (COPD), defined by GOLD as a preventable and treatable disease with some significant extra pulmonary effects, is a very common clinical entity in clinical practice. COPD is associated with significant extra pulmonary (systemic) effects. Systemic inflammation may be mainly driven by risk factor – cigarette smoking and it persists after smoking cessation. COPD is associated with severe extrapulmonary (systemic) manifestations and comorbidities such as cardiac, osteoporosis, gastroesophageal reflux disease, Thyroid Dysfunctions, and obesity. Body mass index (BMI) has also been identified as an independent prognostic factor for COPD.

Aims and Objectives: This study was conducted to determine the proportion of hypothyroidism and obesity in COPD patients and their association with GOLD stage.

Materials and Methods: This was an observational cross-sectional study assessing, COPD patients to determine proportions of thyroid disorder and obesity within a period of 1 year. Data were coded and recorded in MS Excel spreadsheet program. SPSS v23 (IBM Corp.) was used for data analysis.

Results: The following variables were significantly associated (P<0.05) with the variable “GOLD Stage: Weight (kg), BMI, and obesity. 30 (35.3%) COPD patient having abnormal thyroid profile and all 30 (35.3%) were diagnosed as hypothyroid.

Conclusion: From the study, it was found that BMI of patient decreases with increase in GOLD COPD staging. This indicates that obesity might have some protective effect in COPD but this need to be further evaluated.

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Published

2023-11-01

How to Cite

Deepak Singh, Anjuman Chaudhary, Atul Kumar Singh, & Abhishek Singh. (2023). Association of thyroid function and obesity with chronic obstructive pulmonary disease: An observational cross-sectional study. Asian Journal of Medical Sciences, 14(11), 95–100. https://doi.org/10.3126/ajms.v14i11.55662

Issue

Vol. 14 No. 11 (2023)

Section

Original Articles

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Copyright (c) 2023 Asian Journal of Medical Sciences

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