Clinical and demographic profile of peripheral neuropathy in chronic kidney disease in tertiary hospital in Bundelkhand region, Central India

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Keywords:

Chronic kidney disease; Peripheral neuropathy; Pre-hemodialysis

Abstract

Background: Peripheral neuropathy is the most common chronic kidney disease (CKD)-related complication, with a prevalence of more than 60%. It is directly proportional to the duration and severity of CKD.

Aims and Objectives: The study focuses on the prevalence, clinical, and demographic profile of peripheral neuropathy in CKD patients.

Materials and Methods: The present study was cross-sectional and conducted in a tertiary hospital in Central India from October 2021 to September 2022. Among 100 CKD patients, peripheral neuropathy was assessed clinically and by electrophysiological nerve conduction studies.

Results: Out of 100 subjects, 66% were male and 34% were female. Males were affected more (66.66%) than females (58.82%). Out of 46 pre-hemodialysis (HD) patients, 25 (54.34%) showed peripheral neuropathy. Out of 54 HD patients, 41 (75.92%) showed peripheral neuropathy, maximum age group with neuropathy >60 years, duration of uremia of 31–36 months, and average creatinine >9 mg/dL. The most common pattern observed was mixed sensory-motor neuropathy (axonal+demyelination) at 86.36%.

Conclusion: The prevalence of peripheral neuropathy increases with the duration and severity of CKD. The most common pattern is distal symmetrical mixed sensory-motor neuropathy.

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Published

2023-11-01

How to Cite

Sengar NS, Arvind Kankane, Shailja Singh, & Nutan Agrawal. (2023). Clinical and demographic profile of peripheral neuropathy in chronic kidney disease in tertiary hospital in Bundelkhand region, Central India. Asian Journal of Medical Sciences, 14(11), 191–194. Retrieved from https://nepjol.info/index.php/AJMS/article/view/55486

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Section

Original Articles