Triple Negative Breast Cancer-An Overview and Review of Literature

Authors

  • Amit Gupta Dept. of Surgery, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital
  • Jyotika Jain Delhi State Cancer Institute
  • Ajay Kumar Dept. of Surgery, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital
  • Sunil Kumar Dept. of Surgery, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital
  • Neelam Wadhwa Dept. of Pathology, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital

DOI:

https://doi.org/10.3126/ajms.v3i2.5384

Keywords:

breast cancer, triple-negative, estrogen progesterone receptor (PR), Her2/neu receptor

Abstract

Triple-negative breast cancer refers to a specific subtype of breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu. About 12-17 % of ca breast  have triple negative ca breast This subtype of breast cancer is clinically characterized as more aggressive and less responsive to standard treatment and associated with overall poorer prognosis. Chemotherapy is the choice of systemic therapy for triple-negative tumors. They are more susceptible to non-receptor mediated therapies than other tumors. A number of new strategies are currently being tested in clinical trials.

DOI: http://dx.doi.org/10.3126/ajms.v3i2.5384

Asian Journal of Medical Sciences 3(2012) 16-20

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Published

2013-02-26

How to Cite

Gupta, A., Jain, J., Kumar, A., Kumar, S., & Wadhwa, N. (2013). Triple Negative Breast Cancer-An Overview and Review of Literature. Asian Journal of Medical Sciences, 3(2), 16–20. https://doi.org/10.3126/ajms.v3i2.5384

Issue

Vol. 3 No. 2 (2012)

Section

Review Articles

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