Neonatal transfusion-related acute lung injury a rare complication of exchange transfusion - A case report

Authors

DOI:

https://doi.org/10.3126/ajms.v14i5.52062

Keywords:

Neonatal transfusion-related acute lung injury; Exchange transfusion; Unconjugated hyperbilirubinemia

Abstract

Transfusion-related acute lung injury (TRALI), a life-threatening condition, remains an under reported complication, especially among neonates postexchange transfusion for unconjugated hyperbilirubinemia. Appropriate recognition and prompt treatment change the prognosis for good. The present case emphasizes that TRALI must be kept as a differential diagnosis in previously well neonates presenting with sudden onset hypoxia within or during 6 h of transfusion with evidence of bilateral infiltrates on a frontal chest radiograph, and no evidence of circulatory overload, left atrial hypertension, or pre-existing respiratory distress before transfusion. We report the rare occurrence of TRALI and its successful management with supportive hemodynamic management and corrective ventilator strategies.

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Published

2023-05-01

How to Cite

Singh, R., & Atul Kumar Saroj. (2023). Neonatal transfusion-related acute lung injury a rare complication of exchange transfusion - A case report. Asian Journal of Medical Sciences, 14(5), 238–241. https://doi.org/10.3126/ajms.v14i5.52062

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Section

Case Reports